Evidence map›Paper›PMID 18223030›Full record

ArticleDiabetes care2008

Trends in the prevalence of preexisting diabetes and gestational diabetes mellitus among a racially/ethnically diverse population of pregnant women, 1999-2005.

Jean M Lawrence, Richard Contreras, Wansu Chen, David A Sacks

3 registry-linked trialsAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Diabetes care, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 258 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
258citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04523363 phase4withdrawnstarted 2025, after this paper: background citation

Metformin Versus Standard of Care Treatment in Pregnant Women With Prediabetes: A Randomized Trial

Ran2025Enrolled0Registered outcomes21Posted comparisons0ConditionsPrediabetes; Complicating PregnancyArmsMetformin
Open the trial in the graph
NCT02308735 terminatednot on this mapstarted 2014, after this paper: background citation

Fatty Acid Ethyl Esters in Meconium of Infants of Diabetic Mothers: a Pilot Trial

Typeobservational_patient_registrySponsorUniversity of OklahomaRan2014 to 2017Enrolled4ConditionsInfants of Diabetic MothersArmsN/A - No intervention
NCT04801121 unknown statusnot on this mapstarted 2020, after this paper: background citation

Fetal Growth and Placental Function in Pregnancies Complicated by Diabetes

Typeobservational_patient_registrySponsorSidsel Linneberg RathckeRan2020 to 2023Enrolled100ConditionsPregnancy in Diabetics, Placenta, Fetal Growth, Magnetic Resonance Imaging
3 · Its place in the literature

Who cites it

258 citing papers in PubMed, 9 syntheses or guidelines pooled it.

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  17. Pregnancy and Diabetes Racial/Ethnicity Health Disparities in a Large Integrated Health System.Clinical diabetes : a publication of the American Diabetes Association · 2025
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  18. Article
  19. Review
  20. Observational

198 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jean M LawrenceResearch & Evaluation, Kaiser Permanente Southern California, 100 S. Los Robles, 2nd floor, Pasadena, CA 91101, USA. jean.m.lawrence@kp.org
Richard Contreras
Wansu Chen
David A Sacks

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this study was to assess changes in the prevalence of preexisting diabetes (diabetes antedating pregnancy) and gestational diabetes mellitus (GDM) from 1999 through 2005. RESEARCH DESIGN AND

methodsIn this retrospective study of 175,249 women aged 13-58 years with 209,287 singleton deliveries of >or=20 weeks' gestation from 1999 through 2005 in all Kaiser Permanente hospitals in southern California, information from clinical databases and birth certificates was used to estimate the prevalence of preexisting diabetes and GDM.

resultsPreexisting diabetes was identified in 2,784 (1.3%) of all pregnancies, rising from an age- and race/ethnicity-adjusted prevalence of 0.81 per 100 in 1999 to 1.82 per 100 in 2005 (P(trend) < 0.001). Significant increases were observed in all age-groups and all racial/ethnic groups. After women with preexisting diabetes were excluded, GDM was identified in 15,121 (7.6%) of 199,298 screened pregnancies. The age- and race/ethnicity-adjusted GDM prevalence remained constant at 7.5 per 100 in 1999 to 7.4 per 100 in 2005 (P(trend) = 0.07). Among all deliveries to women with either form of diabetes, 10% were due to preexisting diabetes in 1999, rising to 21% in 2005, with GDM accounting for the remainder.

conclusionsThe stable prevalence of GDM and increase in the prevalence of preexisting diabetes were independent of changes in the age and race/ethnicity of the population. The increase in preexisting diabetes, particularly among younger women early in their reproductive years, is of concern.

Indexed as

AdolescentAdultCaliforniaDiabetes, GestationalDiabetes MellitusFemaleGroup PracticeHumansMiddle AgedPregnancyPrevalenceProbabilityRetrospective Studies

Identifiers

PMID18223030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.