ReviewBiology direct2008
The prokaryotic V4R domain is the likely ancestor of a key component of the eukaryotic vesicle transport system.
Review in Biology direct, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- The eukaryotic-like characteristics of small GTPase, roadblock and TRAPPC3 proteins from Asgard archaea.Communications biology · 2024Article
- Article
- A Complex Endomembrane System in the ArchaeonFrontiers in microbiology · 2017Article
- Life on the edge: functional genomic response of Ignicoccus hospitalis to the presence of Nanoarchaeum equitans.The ISME journal · 2015Article
- Redox-sensitive DNA binding by homodimeric Methanosarcina acetivorans MsvR is modulated by cysteine residues.BMC microbiology · 2013Article
- A bird's-eye view of autophagy.Autophagy · 2013Article
- Article
- Planctomycetes and eukaryotes: a case of analogy not homology.BioEssays : news and reviews in molecular, cellular and developmental biology · 2011Article
- The methanogen-specific transcription factor MsvR regulates the fpaA-rlp-rub oxidative stress operon adjacent to msvR in Methanothermobacter thermautotrophicus.Journal of bacteriology · 2010Article
- The origin and early evolution of eukaryotes in the light of phylogenomics.Genome biology · 2010Article
- Happy together: genomic insights into the unique Nanoarchaeum/Ignicoccus association.Journal of biology · 2009Review
- The TRAPP complex: insights into its architecture and function.Traffic (Copenhagen, Denmark) · 2008Review
- The last universal common ancestor: emergence, constitution and genetic legacy of an elusive forerunner.Biology direct · 2008Review
- A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans.Genome biology · 2008Article
- Molecular paleontology and complexity in the last eukaryotic common ancestor.Critical reviews in biochemistry and molecular biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Intracellular vesicle traffic that enables delivery of proteins between the endoplasmic reticulum, Golgi and various endosomal subcompartments is one of the hallmarks of the eukaryotic cell. Its evolutionary history is not well understood but the process itself and the core vesicle traffic machinery are believed to be ancient. We show here that the 4-vinyl reductase (V4R) protein domain present in bacteria and archaea is homologous to the Bet3 subunit of the TRAPP1 vesicle-tethering complex that is conserved in all eukaryotes. This suggests, for the first time, a prokaryotic origin for one of the key eukaryotic trafficking proteins.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.