ArticleGlycoconjugate journal2008
Sequence determination of a non-sulfated glycosaminoglycan-like polysaccharide from melanin-free ink of the squid Ommastrephes bartrami by negative-ion electrospray tandem mass spectrometry and NMR spectroscopy.
Article in Glycoconjugate journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 68 citations in OpenAlex.
- Polysaccharides fromCurrent medicinal chemistry · 2026Article
- Bioactive Polysaccharides from FermentedMolecules (Basel, Switzerland) · 2025Article
- Antimicrobial and cytotoxic activities of flavonoid and phenolics extracted from Sepia pharaonis ink (Mollusca: Cephalopoda).BMC biotechnology · 2024Article
- Insights into Common Octopus (Marine drugs · 2023Article
- Effect of steaming process on the structural characteristics and antioxidant activities of polysaccharides from Polygonatum sibiricum rhizomes.Glycoconjugate journal · 2021Article
- Highly sialylated mucin-type glycopeptide from porcine intestinal mucosa after heparin extraction: O-glycan profiling and immunological activity evaluation.Glycoconjugate journal · 2021Article
- Alkaline Extraction, Structural Characterization, and Bioactivities of (1→6)-β-d-Glucan fromMolecules (Basel, Switzerland) · 2019Article
- Profiling and Structural Characterization of High Neu5Gc or Sulfate-containing O-glycans from Hyla Rabbit Intestinal Mucin.Molecules (Basel, Switzerland) · 2019Article
- Structure and Neuroprotective Effect of Polysaccharide from Viscera Autolysates of SquidMarine drugs · 2019Article
- Structural Characterization and Interaction with RCAMarine drugs · 2018Article
- A Potential Adjuvant Agent of Chemotherapy: Sepia Ink Polysaccharides.Marine drugs · 2018Review
- Inhibition of chemotherapy-induced apoptosis of testicular cells by squid ink polysaccharide.Experimental and therapeutic medicine · 2017Article
- Squid ink polysaccharide prevents autophagy and oxidative stress affected by cyclophosphamide in Leydig cells of mice: a pilot study.Iranian journal of basic medical sciences · 2017Article
- Polysaccharide fromIranian journal of basic medical sciences · 2016Article
- Squid ink polysaccharide reduces cyclophosphamide-induced testicular damage via Nrf2/ARE activation pathway in mice.Iranian journal of basic medical sciences · 2015Article
- Extraction, Isolation, Structural Characterization and Anti-Tumor Properties of an Apigalacturonan-Rich Polysaccharide from the Sea Grass Zostera caespitosa Miki.Marine drugs · 2015Article
- Preparation of water-soluble melanin from squid ink using ultrasound-assisted degradation and its anti-oxidant activity.Journal of food science and technology · 2014Article
- Isolation and structure characterization of an antioxidative glycopeptide from mycelial culture broth of a medicinal fungus.International journal of molecular sciences · 2014Article
- Applications of mass spectrometry to structural analysis of marine oligosaccharides.Marine drugs · 2014Review
- Cephalopod ink: production, chemistry, functions and applications.Marine drugs · 2014Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 3 countries.
Funding
Abstract
A non-sulfated polysaccharide was isolated from the ink sac of squid Ommastrephes bartrami after removal of the melanin granules. The carbohydrate sequence of this polysaccharide was assigned by negative-ion electrospray tandem mass spectrometry with collision-induced dissociation of the oligosaccharide fractions produced by partial acid hydrolysis of the polysaccharide. The structural determination was completed by NMR for assignment of anomeric configuration and confirmation of linkage information and it was unambiguously identified as a glycosaminoglycan-like polysaccharide containing a glucuronic acid-fucose (GlcA-Fuc) disaccharide repeat in the main chain and a N-acetylgalactosamine (GalNAc) branch at Fuc position 3: -[3GlcAbeta1-4(GalNAcalpha1-3)Fucalpha1](n)-. Partial hydrolysis of the polysaccharide to obtain several oligosaccharide fractions with different numbers of the repeating unit assisted the assignment. In the negative-ion tandem mass spectrometric analysis, the unique (0,2)A type fragmentation was important to establish the presence of a 4-linked fucose in the main polysaccharide chain and a GalNAc branch at the Fuc position-3 of the disaccharide repeat.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.