ReviewJournal of mammary gland biology and neoplasia2008
Paradigm-shifters: phosphorylated prolactin and short prolactin receptors.
Review in Journal of mammary gland biology and neoplasia, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- B lymphoproliferative diseases: Effective treatment, inhibited progression, and potential cures through isoform-specific targeting of the prolactin receptor.Vitamins and hormones · 2025Review
- Multiple cell types in the oviduct express the prolactin receptor.FASEB bioAdvances · 2022Article
- Orchestration of signaling by structural disorder in class 1 cytokine receptors.Cell communication and signaling : CCS · 2020Article
- Functional consequences of prolactin signalling in endothelial cells: a potential link with angiogenesis in pathophysiology?Journal of cellular and molecular medicine · 2012Article
- Prolactin and dexamethasone regulate second messenger-stimulated cl(-) secretion in mammary epithelia.Journal of signal transduction · 2012Article
- Inhibition of MAPK by prolactin signaling through the short form of its receptor in the ovary and decidua: involvement of a novel phosphatase.The Journal of biological chemistry · 2011Article
- Effects of prolactin on TSC2-null Eker rat cells and in pulmonary lymphangioleiomyomatosis.American journal of respiratory and critical care medicine · 2010Article
- Introduction: hormonal regulation of mammary development and milk protein gene expression at the whole animal and molecular levels.Journal of mammary gland biology and neoplasia · 2009Article
- Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues.Reproductive biology and endocrinology : RB&E · 2009Article
- Regulation of transcription factors and repression of Sp1 by prolactin signaling through the short isoform of its cognate receptor.Endocrinology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the discovery of physiologically-regulated prolactin (PRL) phosphorylation, one focus of the laboratory has been an examination of the different functions of the unmodified and phosphorylated hormone. In the mammary gland, unmodified PRL promotes growth activities, whereas phosphorylated or pseudophosphorylated PRL antagonizes this while also being a superior agonist for changes that favor differentiation. Phosphorylated PRL also increases expression of the short forms of the PRL receptor. These short forms of the receptor have functions beyond the accepted dominant negative and in mammary epithelial cells are capable of generating an intracellular signal leading to increased tight junction formation and beta-casein expression.
Indexed as
Identifiers
18219563What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.