ArticleVirology journal2008
Avian influenza: genetic evolution under vaccination pressure.
Article in Virology journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed.
- Novel Reassortant H5N2 Highly Pathogenic Avian Influenza Viruses from Backyard Poultry in Mexico.Viruses · 2026Article
- Antiviral potentials of garlic (Allium sativum) in poultry production: A mini review.Veterinary medicine and science · 2023Review
- Avian influenza revisited: concerns and constraints.Virusdisease · 2022Review
- Article
- Discrepancies in the efficacy of H5 inactivated avian influenza vaccines in specific-pathogen-free chickens against challenge with the Egyptian H5N8 clade 2.3.4.4 Group B virus isolated in 2018.Veterinary world · 2021Article
- A quantitative risk assessment to evaluate the efficacy of mitigation strategies to reduce highly pathogenic avian influenza virus, subtype H5N1 (HPAI H5N1) in the Menoufia governorate, Egypt.BMC veterinary research · 2021Article
- Low Pathogenicity Avian Influenza (H5N2) Viruses, Dominican Republic.Emerging infectious diseases · 2020Article
- Global patterns of avian influenza A (H7): virus evolution and zoonotic threats.FEMS microbiology reviews · 2019Review
- A hospital cluster combined with a family cluster of avian influenza H7N9 infection in Anhui Province, China.The Journal of infection · 2019Article
- Geographical and Historical Patterns in the Emergences of Novel Highly Pathogenic Avian Influenza (HPAI) H5 and H7 Viruses in Poultry.Frontiers in veterinary science · 2018Article
- Evolution and Vaccination of Influenza Virus.Journal of computational biology : a journal of computational molecular cell biology · 2017Article
- Genetic and antigenic characterization of influenza A(H3N2) in Cameroon during the 2014-2016 influenza seasons.PloS one · 2017Article
- Highly Pathogenic Avian Influenza Virus A/H5N1 Infection in Vaccinated Meat Duck Flocks in the Mekong Delta of Vietnam.Transboundary and emerging diseases · 2016Article
- Inhibiting avian influenza virus shedding using a novel RNAi antiviral vector technology: proof of concept in an avian cell model.AMB Express · 2016Article
- Protective efficacy of stockpiled vaccine against H5N8 highly pathogenic avian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in 2014.The Journal of veterinary medical science · 2016Article
- Role of vaccination-induced immunity and antigenic distance in the transmission dynamics of highly pathogenic avian influenza H5N1.Journal of the Royal Society, Interface · 2016Article
- Article
- Variation in protection of four divergent avian influenza virus vaccine seed strains against eight clade 2.2.1 and 2.2.1.1. Egyptian H5N1 high pathogenicity variants in poultry.Influenza and other respiratory viruses · 2014Article
- Molecular characterization of avian influenza H5N1 virus in Egypt and the emergence of a novel endemic subclade.The Journal of general virology · 2014Article
- Success factors for avian influenza vaccine use in poultry and potential impact at the wild bird-agricultural interface.EcoHealth · 2014Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antigenic drift of avian influenza viruses (AIVs) has been observed in chickens after extended vaccination program, similar to those observed with human influenza viruses. To evaluate the evolutionary properties of endemic AIV under high vaccination pressure (around 2 billion doses used in the last 12 years), we performed a pilot phylogenic analysis of the hemagglutinin (HA) gene of AIVs isolated from 1994 to 2006. This study demonstrates that Mexican low pathogenicity (LP) H5N2-AIVs are constantly undergoing genetic drifts. Recent AIV isolates (2002-2006) show significant molecular drifts when compared with the H5N2 vaccine-strain or other field isolates (1994-2000). This study also demonstrates that molecular drifts in the HA gene lineages follow a yearly trend, suggesting gradually cumulative sequence mutations. These findings might explain the increasing incidence of LP H5N2 AIV isolated from commercial avian farms. These findings support recent concerns about the challenge of AIV antigenic drift and influenza epidemics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.