Evidence map›Paper›PMID 18218040›Full record

ArticleEuropean journal of clinical investigation2008

Iron overload in myelodysplastic syndromes (MDS) - diagnosis, management, and response criteria: a proposal of the Austrian MDS platform.

P Valent, O Krieger, R Stauder, F Wimazal, T Nösslinger, W R Sperr, H Sill, P Bettelheim, M Pfeilstöcker

Open access · bronzeAbstract read
In one paragraph

Article in European journal of clinical investigation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

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  14. Myelodysplastic syndromes: diagnosis, prognosis, and treatment.Deutsches Arzteblatt international · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

P ValentDepartment of Internal Medicine I, Division of Haematology & Haemostaseology, Medical University of Vienna, Austria. peter.valent@meduniwien.ac.at
O Krieger
R Stauder
F Wimazal
T Nösslinger
W R Sperr
H Sill
P Bettelheim
M Pfeilstöcker
Medical University of Vienna · ATHanusch Hospital · ATInnsbruck Medical University · ATKrankenhaus der Elisabethinen · ATMedical University of Graz · ATOtto Wagner Hospital · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transfusion-related morbidity is an emerging challenge in chronically transfused patients with low-risk myelodysplastic syndromes (MDS). In these patients, transfusion-induced iron overload may represent a leading medical problem. However, although iron-chelating drugs are available, little is known about optimal diagnostic tools, predisposing factors, and the optimal management of these patients. In the current article, we provide recommendations for the diagnosis, prevention and treatment of iron overload in MDS and propose treatment response criteria. Consensus criteria and resulting recommendations were discussed and formulated by members of the MDS platform of the Austrian Society of Haematology and Oncology in a series of meetings and conferences in 2006 and 2007. These recommendations should facilitate and assist in recognition of iron overload, selection of patients, timing of treatment, drug selection and the measurement of treatment responses.

Indexed as

Chelation TherapyErythrocyte TransfusionFerritinsGuidelines as TopicHumansIron Chelating AgentsIron OverloadMyelodysplastic SyndromesFerritinsIron Chelating Agents

Identifiers

PMID18218040
PMCPMC2438601
OpenAlexW1983215575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.