ArticleEmerging infectious diseases2007
Canonical insertion-deletion markers for rapid DNA typing of Francisella tularensis.
Article in Emerging infectious diseases, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Development of a Real-Time PCR Assay for the Detection ofMicroorganisms · 2024Article
- Tularemia - a re-emerging disease with growing concern.The veterinary quarterly · 2023Article
- Tularemia Outbreaks in Spain from 2007 to 2020 in Humans and Domestic and Wild Animals.Pathogens (Basel, Switzerland) · 2021Article
- Tularemia Goes West: Epidemiology of an Emerging Infection in Austria.Microorganisms · 2020Review
- Optimized MALDI TOF Mass Spectrometry Identification ofMicroorganisms · 2020Article
- Genome-wide functional association networks: background, data & state-of-the-art resources.Briefings in bioinformatics · 2020Review
- Phylogeographic Distribution of Human and HareFrontiers in cellular and infection microbiology · 2019Article
- Phylogenetic Lineages ofFrontiers in cellular and infection microbiology · 2018Review
- Long-Lasting Fever and Lymphadenitis: Think about F. tularensis.Case reports in medicine · 2015Article
- Molecular investigation of tularemia outbreaks, Spain, 1997-2008.Emerging infectious diseases · 2014Article
- Tularaemia: a challenging zoonosis.Comparative immunology, microbiology and infectious diseases · 2014Review
- Insights to genetic characterization tools for epidemiological tracking of Francisella tularensis in Sweden.PloS one · 2014Article
- Article
- Increased knowledge of Francisella genus diversity highlights the benefits of optimised DNA-based assays.BMC microbiology · 2012Article
- Differential chitinase activity and production within Francisella species, subspecies, and subpopulations.Journal of bacteriology · 2011Article
- Phylogeography of Francisella tularensis subspecies holarctica from the country of Georgia.BMC microbiology · 2011Article
- Molecular Detection of Persistent Francisella tularensis Subspecies holarctica in Natural Waters.International journal of microbiology · 2011Article
- Article
- Article
- Identification of Francisella tularensis cluster in central and western Europe.Emerging infectious diseases · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To develop effective and accurate typing of strains of Francisella tularensis, a potent human pathogen and a putative bioterrorist agent, we combined analysis of insertion-deletion (indel) markers with multiple-locus variable-number tandem repeat analysis (MLVA). From 5 representative F. tularensis genome sequences, 38 indel markers with canonical properties, i.e., capable of sorting strains into major genetic groups, were selected. To avoid markers with a propensity for homoplasy, we used only those indels with 2 allelic variants and devoid of substantial sequence repeats. MLVA included sequences with much diversity in copy number of tandem repeats. The combined procedure allowed subspecies division, delineation of clades A.I and A.II of subspecies tularensis, differentiation of Japanese strains from other strains of subspecies holarctica, and high-resolution strain typing. The procedure uses limited amounts of killed bacterial preparations and, because only 1 single analytic method is needed, is time- and cost-effective.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.