Evidence map›Paper›PMID 18216768›Full record

ReviewNature reviews. Molecular cell biology2008

Membrane lipids: where they are and how they behave.

Gerrit van Meer, Dennis R Voelker, Gerald W Feigenson

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Molecular cell biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3,217 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3,217citing papers in PubMed, 1 pooled it
72.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3,217 citing papers in PubMed, 1 synthesis or guideline pooled it, 6,994 citations in OpenAlex.

  1. Pooled it
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  4. Virulence · 2026
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3,157 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Gerrit van MeerBijvoet Center and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands. g.vanmeer@uu.nl
Dennis R Voelker
Gerald W Feigenson
Cornell University · USUniversity of Colorado Denver · USUtrecht University · NL

Funding

Membrane Control of Protein-Protein Contact. Simulation Based on Phase DiagramsR01GM077198 · NIGMS · CORNELL UNIVERSITY · PI FEIGENSON, GERALD WILLIAM · 2007 to 2010
$1.6M
NIGMS NIH HHS R01 GM077198
6 · The paper itself

Abstract

Throughout the biological world, a 30 A hydrophobic film typically delimits the environments that serve as the margin between life and death for individual cells. Biochemical and biophysical findings have provided a detailed model of the composition and structure of membranes, which includes levels of dynamic organization both across the lipid bilayer (lipid asymmetry) and in the lateral dimension (lipid domains) of membranes. How do cells apply anabolic and catabolic enzymes, translocases and transporters, plus the intrinsic physical phase behaviour of lipids and their interactions with membrane proteins, to create the unique compositions and multiple functionalities of their individual membranes?

Indexed as

AnimalsBiochemistryBiophysicsCell MembraneCytosolGolgi ApparatusHumansLipid BilayersLipidsModels, BiologicalPhosphatidylcholinesProtein TransportLipid BilayersLipidsPhosphatidylcholines

Identifiers

PMID18216768
PMCPMC2642958
OpenAlexW2125872855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.