ArticleAnnals of plastic surgery2008
The effect of cleft palate repair on contractile properties of single permeabilized muscle fibers from congenitally cleft goat palates.
Article in Annals of plastic surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- A new congenital cleft palate New Zealand rabbit model for surgical research.Scientific reports · 2021Article
- Power output of skinned skeletal muscle fibres from the cheetah (Acinonyx jubatus).The Journal of experimental biology · 2013Article
- Strategies to improve regeneration of the soft palate muscles after cleft palate repair.Tissue engineering. Part B, Reviews · 2012Review
- The effect of cleft palate repair on contractile properties of single permeabilized muscle fibers from congenitally cleft goat palates.Annals of plastic surgery · 2008Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
Abstract
Inherent differences in the levator veli palatini (LVP) muscle of cleft palates before palatoplasty may play a role in persistent postrepair velopharyngeal insufficiency (VPI). Contractile properties of LVP muscle fibers were analyzed from young (2-month) normal (YNP), young congenitally cleft (YCP) and again on the same YCP subjects 6 months after palatoplasty, mature repaired palate (MRP). The cross-sectional area and rate of force development (ktr) were measured. Specific force (sF(0)) and normalized power (nP(max)) were calculated. Using k(tr) to determine fiber type composition, YNP was 44% type 1 and 56% type 2, while YCP was 100% type 2. Two MRP subjects shifted to 100% type 1; 1 demonstrated increased resistance to fatigue. No differences in sF(0) were observed. nP(max) increased with presence of type 2 fibers. The persistent state of type 2 fibers following palatoplasty leads to increased fatigue in the LVP of MRP subjects and may cause VPI symptoms.
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Registered trials
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