ArticleThe New England journal of medicine2008
Chimerism and tolerance in a recipient of a deceased-donor liver transplant.
Article in The New England journal of medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 159 citations in OpenAlex.
- Circulating hematopoietic stem/progenitor cell subsets contribute to human hematopoietic homeostasis.Blood · 2024Trial
- Donor macrophage depletion permits posttransplant tolerance induction in a murine islet transplant model.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026Article
- Redefining post-xenotransplantation surveillance: leveraging metagenomic next-generation sequencing to discriminate true pathogen replication from microchimerism-induced false positives.Clinical transplantation and research · 2026Review
- Microchimerism and the need to rethink sex and gender binaries.Biology of sex differences · 2025Review
- Lung stem cells and respiratory epithelial chimerism in transplantation.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Tolerance Induction Strategies in Organ Transplantation: Current Status and Future Perspectives.Transplant international : official journal of the European Society for Organ Transplantation · 2025Review
- Donor and recipient hematopoietic stem and progenitor cells mobilization in liver transplantation patients.Stem cell research & therapy · 2024Article
- Cellular strategies to induce immune tolerance after liver transplantation: Clinical perspectives.World journal of gastroenterology · 2024Article
- Exploring extramedullary hematopoiesis: unraveling the hematopoietic microenvironments.Frontiers in hematology · 2024Article
- Biomaterials-based immunomodulation enhances survival of murine vascularized composite allografts.Biomaterials science · 2023Article
- Case Report: Liver as a Source of Hematopoietic Stem Cells After Liver Transplantation Following Hematopoietic Stem Cell Transplantation.Frontiers in pediatrics · 2022Article
- Therapy-related myeloid neoplasms after transcatheter arterial chemoembolization for hepatocellular carcinoma.Blood research · 2021Article
- Antigen Specific Regulatory T Cells in Kidney Transplantation and Other Tolerance Settings.Frontiers in immunology · 2021Review
- The Immunological Basis of Liver Allograft Rejection.Frontiers in immunology · 2020Review
- Progress in Liver Transplant Tolerance and Tolerance-Inducing Cellular Therapies.Frontiers in immunology · 2020Review
- Healing the Broken Heart; The Immunomodulatory Effects of Stem Cell Therapy.Frontiers in immunology · 2020Review
- Harnessing immunotherapy for liver recipients with hepatocellular carcinoma: a review from a transplant oncology perspective.Therapeutic advances in medical oncology · 2019Review
- [When A is not A anymore: problems and pitfalls with blood group typing].Der Anaesthesist · 2018Review
- Mechanisms of Mixed Chimerism-Based Transplant Tolerance.Trends in immunology · 2017Review
- Early Chimerism After Liver Transplantation Reflects the Clinical Course of Recurrent Hepatitis C.Annals of transplantation · 2017Article
Corrections and comments
- Commented on by
- Commented on by
- Commented on by
Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Complete hematopoietic chimerism and tolerance of a liver allograft from a deceased male donor developed in a 9-year-old girl, with no evidence of graft-versus-host disease 17 months after transplantation. The tolerance was preceded by a period of severe hemolysis, reflecting partial chimerism that was refractory to standard therapies. The hemolysis resolved after the gradual withdrawal of all immunosuppressive therapy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.