Evidence map›Paper›PMID 18214517›Full record

ReviewHistochemistry and cell biology2008

Morphogenesis of post-Golgi transport carriers.

Alberto Luini, Alexander A Mironov, Elena V Polishchuk, Roman S Polishchuk

Open access · hybridAbstract readReview
In one paragraph

Review in Histochemistry and cell biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. The Diffusion Model of Intra-Golgi Transport Has Limited Power.International journal of molecular sciences · 2023
    Article
  3. Review
  4. Article
  5. Microtubules in Pancreatic β Cells: Convoluted Roadways Toward Precision.Frontiers in cell and developmental biology · 2022
    Review
  6. Article
  7. Review
  8. Models of Intracellular Transport: Pros and Cons.Frontiers in cell and developmental biology · 2019
    Article
  9. Intracellular trafficking pathways of Cx43 gap junction channels.Biochimica et biophysica acta. Biomembranes · 2018
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alberto LuiniDepartment of Cell Biology and Oncology, Consorzio Mario Negri Sud, 66030, Santa Maria Imbaro (Chieti), Italy. luini@negrisud.it
Alexander A Mironov
Elena V Polishchuk
Roman S Polishchuk
Mario Negri Sud Foundation · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The trans-Golgi network (TGN) is one of the main, if not the main, sorting stations in the process of intracellular protein trafficking. It is therefore of central importance to understand how the key players in the TGN-based sorting and delivery process, the post-Golgi carriers (PGCs), form and function. Over the last few years, modern morphological approaches have generated new insights into the questions of PGC biogenesis, structure and dynamics. Here, we present a view by which the "lifecycle" of a PGC consists of several distinct stages: the formation of TGN tubular export domains (where different cargoes are segregated from each other and from the Golgi enzymes); the docking of these tubular domains onto molecular motors and their extrusion towards the cell periphery along microtubules; the fission of the forming PGC from the donor membrane; and the delivery of the newly formed PGC to its specific acceptor organelle. It is now important to add the many molecular machineries that have been described as operating at the TGN to this "morphofunctional map" of the TGN export process.

Indexed as

AnimalsBiological TransportHumanstrans-Golgi NetworkTransport Vesicles

Identifiers

PMID18214517
PMCPMC2228382
OpenAlexW2093985037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.