Evidence map›Paper›PMID 18212350›Full record

ReviewReproductive sciences (Thousand Oaks, Calif.)2008

Racial differences in nitric oxide-dependent vasorelaxation.

Eugenia Mata-Greenwood, Dong-Bao Chen

Open access · greenAbstract readReview
In one paragraph

Review in Reproductive sciences (Thousand Oaks, Calif.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. The effect of acute administration of vitamin D on micro vascular endothelial function in Caucasians and South Asian Indians.Medical science monitor : international medical journal of experimental and clinical research · 2013
    Trial
  7. Blindspot: how sun exposure guidelines have ignored the health of individuals with skin of color.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Review
  8. Article
  9. Hydrogen sulfide and its role in female reproduction.Frontiers in veterinary science · 2024
    Review
  10. Article
  11. Review
  12. Article
  13. Racial disparities in cardiovascular disease risk: mechanisms of vascular dysfunction.American journal of physiology. Heart and circulatory physiology · 2019
    Review
  14. Article
  15. Article
  16. Review
  17. Hypertension in African Americans.Current cardiology reports · 2017
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Eugenia Mata-GreenwoodDepartment of Reproductive Medicine, University of California, San Diego, USA. ematagreenwood@llu.edu.
Dong-Bao Chen
University of California, San Diego · US

Funding

Actions of Estrogen on Uterine Artery EndotheliumR01HL070562 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHEN, DONGBAO · 2001 to 2025
$6.3M
Caveolin-1, Caveolae and Placental AngiogenesisR01HL074947 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHEN, DONGBAO · 2004 to 2007
$1.3M
NHLBI NIH HHS HL74947NHLBI NIH HHS R01 HL070562NHLBI NIH HHS R01 HL074947NHLBI NIH HHS R01 HL 70562
6 · The paper itself

Abstract

Along with the growing heterogeneity of the American population, ethnic/racial disparity is becoming a clear health issue in the United States. The awareness of ethnic/racial disparities has been growing because of considerable data gathered from recent clinical and epidemiological studies. These studies have highlighted the importance of addressing these differences in the diagnosis and treatment of various diseases potentially according to race. It is becoming particularly clear that there is a 2- to 3-fold racial difference in certain cardiovascular diseases (eg, preeclampsia) associated with dysfunctional nitric oxide-mediated vasodilation. In this review, the authors summarize the current literature on racial disparities in nitric oxide-mediated vasodilation in relation to cardiovascular health with an emphasis on vascular nitric oxide bioavailability as a balance between production via endothelial nitric oxide synthase and degradation through reactive oxygen species. The major hypotheses postulated on the biological basis of these differences are also highlighted.

Indexed as

Black or African AmericanVasodilationWhite PeopleCardiovascular DiseasesFemaleHumansNitric OxidePre-EclampsiaPregnancyNitric Oxide

Identifiers

PMID18212350
PMCPMC2459254
OpenAlexW1998224034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.