ReviewHypertension (Dallas, Tex. : 1979)2008
WNK kinases and renal sodium transport in health and disease: an integrated view.
Review in Hypertension (Dallas, Tex. : 1979), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Mechanistic target of rapamycin complex-1 plays a role in inhibiting kidney KAmerican journal of physiology. Renal physiology · 2026Article
- Deletion of KS-WNK1 promotes NCC activation by increasing WNK1/4 abundance.American journal of physiology. Renal physiology · 2024Article
- Calcineurin inhibitors stimulate Kir4.1/Kir5.1 of the distal convoluted tubule to increase NaCl cotransporter.JCI insight · 2023Article
- The Integral Role of Chloride & With-No-Lysine Kinases in Cell Volume Regulation & Hypertension.International journal of nephrology and renovascular disease · 2023Review
- Summary of Known Genetic and Epigenetic Modification Contributed to Hypertension.International journal of hypertension · 2023Review
- Fucoidan Ameliorates Renal Injury-Related Calcium-Phosphorus Metabolic Disorder and Bone Abnormality in the CKD-MBD Model Rats by Targeting FGF23-Klotho Signaling Axis.Frontiers in pharmacology · 2020Article
- Responses of distal nephron NaAmerican journal of physiology. Renal physiology · 2017Article
- NHA2 is expressed in distal nephron and regulated by dietary sodium.Journal of physiology and biochemistry · 2017Article
- Small-molecule WNK inhibition regulates cardiovascular and renal function.Nature chemical biology · 2016Article
- Src-family protein tyrosine kinase phosphorylates WNK4 and modulates its inhibitory effect on KCNJ1 (ROMK).Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- FGF23 promotes renal calcium reabsorption through the TRPV5 channel.The EMBO journal · 2014Article
- WNK4 inhibits Ca(2+)-activated big-conductance potassium channels (BK) via mitogen-activated protein kinase-dependent pathway.Biochimica et biophysica acta · 2013Article
- MicroRNA regulation in renal pathophysiology.International journal of molecular sciences · 2013Article
- Key developments in renin-angiotensin-aldosterone system inhibition.Nature reviews. Nephrology · 2013Review
- Enhanced phosphorylation of Na(+)-Cl- co-transporter in experimental metabolic syndrome: role of insulin.Clinical science (London, England : 1979) · 2012Article
- Aldosterone does not require angiotensin II to activate NCC through a WNK4-SPAK-dependent pathway.Pflugers Archiv : European journal of physiology · 2012Article
- The role of the ENaC-regulatory complex in aldosterone-mediated sodium transport.Molecular and cellular endocrinology · 2012Review
- Dietary salt modulates the sodium chloride cotransporter expression likely through an aldosterone-mediated WNK4-ERK1/2 signaling pathway.Pflugers Archiv : European journal of physiology · 2012Article
- Genomic-derived markers for early detection of calcineurin inhibitor immunosuppressant-mediated nephrotoxicity.Toxicological sciences : an official journal of the Society of Toxicology · 2011Article
- The WNK kinase network regulating sodium, potassium, and blood pressure.Journal of the American Society of Nephrology : JASN · 2011Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.