ArticleAnnals of clinical microbiology and antimicrobials2008
Comprehensive bactericidal activity of an ethanol-based hand gel in 15 seconds.
Article in Annals of clinical microbiology and antimicrobials, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 52 citations in OpenAlex.
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- Prediction of cell migration potential on human breast cancer cells treated with Albizia lebbeck ethanolic extract using extreme machine learning.Scientific reports · 2023Article
- Efficacy of a New Alcohol-Free Organic Acid-Based Hand Sanitizer against Foodborne Pathogens.Toxics · 2023Article
- Hand Sanitizer Gels: Classification, Challenges, and the Future of Multipurpose Hand Hygiene Products.Toxics · 2023Review
- Prediction of Cell Migration in MDA-MB 231 and MCF-7 Human Breast Cancer Cells Treated withPharmaceuticals (Basel, Switzerland) · 2023Article
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- Optimization of the Process of Eliminating Microorganisms Harmful to Human Health and Threatening Objects Isolated from Historical Materials from the Auschwitz-Birkenau State Museum in Poland (A-BSM) Collection with the Use of Ethanol in the Form of Mist.Materials (Basel, Switzerland) · 2023Article
- Potential and Metabolic Pathways of Eugenol in the Management ofInternational journal of molecular sciences · 2022Article
- Bactericidal and virucidal activity of ethanol and povidone-iodine.MicrobiologyOpen · 2020Review
- ManagingHeliyon · 2020Article
- Survival of outbreak, food, and environmental strains of Listeria monocytogenes on whole apples as affected by cultivar and wax coating.Scientific reports · 2019Article
- Sources of variability in SERS spectra of bacteria: comprehensive analysis of interactions between selected bacteria and plasmonic nanostructures.Analytical and bioanalytical chemistry · 2019Article
- Efficacy of surface disinfectant cleaners against emerging highly resistant gram-negative bacteria.BMC infectious diseases · 2014Article
- Influence of rub-in technique on required application time and hand coverage in hygienic hand disinfection.BMC infectious diseases · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSome studies indicate that the commonly recommended 30 s application time for the post contamination treatment of hands may not be necessary as the same effect may be achieved with some formulations in a shorter application time such as 15 s.
methodWe evaluated the bactericidal activity of an ethanol-based hand gel (Sterillium Comfort Gel) within 15 s in a time-kill-test against 11 Gram-positive, 16 Gram-negative bacteria and 11 emerging bacterial pathogens. Each strain was evaluated in quadruplicate.
resultsThe hand gel (85% ethanol, w/w) was found to reduce all 11 Gram-positive and all 16 Gram-negative bacteria by more than 5 log10 steps within 15 s, not only against the ATCC test strains but also against corresponding clinical isolates. In addition, a log10 reduction > 5 was observed against all tested emerging bacterial pathogens.
conclusionThe ethanol-based hand gel was found to have a broad spectrum of bactericidal activity in only 15 s which includes the most common species causing nosocomial infections and the relevant emerging pathogens. Future research will hopefully help to find out if a shorter application time for the post contamination treatment of hands provides more benefits or more risks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.