ArticleJournal of pediatric surgery2008
Improved survival in a multidisciplinary short bowel syndrome program.
Article in Journal of pediatric surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 61 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Tolerability of an Amino Acid-based Oral Rehydration Solution in Children With Short Bowel Syndrome
Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure
Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it, 222 citations in OpenAlex.
- Working group reports: evaluation of the evidence to support practice guidelines for nutritional care of preterm infants-the Pre-B Project.The American journal of clinical nutrition · 2016Pooled it
- Cisapride improves enteral tolerance in pediatric short-bowel syndrome with dysmotility.Journal of pediatric gastroenterology and nutrition · 2011Trial
- Current state of neonatal intestinal rehabilitation care in North America: A descriptive survey-based study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Article
- Clinical guideline for postoperative nutrition support in neonates with enterostomy (2024).Pediatric investigation · 2025Article
- Factors associated with accelerated parenteral weaning in children with intestinal failure: A descriptive cohort study.JPEN. Journal of parenteral and enteral nutrition · 2025Article
- Retrospective review of growth in pediatric intestinal failure after weaning from parenteral nutrition.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025Article
- Xenotransplanted human organoids identify transepithelial zinc transport as a key mediator of intestinal adaptation.Nature communications · 2024Article
- Normothermic Preservation of the Intestinal Allograft.Gastroenterology clinics of North America · 2024Review
- Ileal lengthening through internal distraction: A novel procedure for ultrashort bowel syndrome.Journal of pediatric surgery open · 2024Article
- Clinical challenges of short bowel syndrome and the path forward for organoid-based regenerative medicine.Regenerative therapy · 2023Review
- Real-world etiologies and treatments of pediatric short bowel syndrome in Japan.Pediatrics international : official journal of the Japan Pediatric Society · 2022Observational
- Multi-Center Analysis of Predictive Factors of Enteral Autonomy and Risk Factors of Complications of Pediatric Intestinal Failure in China.Frontiers in pediatrics · 2022Article
- Article
- Intestinal adaptation following spring insertion into a roux limb in mice.Journal of pediatric surgery · 2021Article
- Short bowel syndrome in infancy: recent advances and practical management.Frontline gastroenterology · 2021Article
- Loss of Slfn3 induces a sex-dependent repair vulnerability after 50% bowel resection.American journal of physiology. Gastrointestinal and liver physiology · 2021Article
- Effects of high-fat diet on liver injury after small bowel resection.Journal of pediatric surgery · 2020Article
- The Role of a Nutrition Support Team in the Management of Intestinal Failure Patients.Nutrients · 2020Review
- EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis.PloS one · 2020Article
- Multidisciplinary Management in Pediatric Ultrashort Bowel Syndrome.Journal of multidisciplinary healthcare · 2020Review
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
purposePediatric short bowel syndrome (SBS) remains a management challenge with significant mortality. In 1999, we initiated a multidisciplinary pediatric intestinal rehabilitation program. The purpose of this study was to determine if the multidisciplinary approach was associated with improved survival in this patient population.
methodsThe Center for Advanced Intestinal Rehabilitation includes dedicated staff in surgery, gastroenterology, nutrition, pharmacy, nursing, and social work. We reviewed the medical records of all inpatients and outpatients with severe SBS treated from 1999 to 2006. These patients were compared to a historical control group of 30 consecutive patients with severe SBS who were treated between 1986 and 1998.
resultsFifty-four patients with severe SBS managed by the multidisciplinary program were identified. Median follow-up was 403 days. The mean residual small intestinal length was 70 +/- 36 vs 83 +/- 67 cm in the historical controls (P = NS). Mean peak direct bilirubin was 8.1 +/- 7.9 vs 9.0 +/- 7.4 mg/dL in controls (P = NS). Full enteral nutrition was achieved in 36 (67%) of 54 patients with severe SBS vs 20 (67%) of 30 patients in the control group (P = NS). The overall survival rate, however, was 89% (48/54), which is significantly higher than in the historical controls (70%, 21/30; P < .05).
conclusionsA multidisciplinary approach to intestinal rehabilitation allows for fully integrated care of inpatients and outpatients with SBS by fostering coordination of surgical, medical, and nutritional management. Our experience with 2 comparable cohorts demonstrates that this multidisciplinary approach is associated with improved survival.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.