ArticleWiener medizinische Wochenschrift (1946)2007
T-plus Z-score in the assessment of relative fracture risk.
Article in Wiener medizinische Wochenschrift (1946), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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- Metabolic bone diseases: basic and clinical aspects.Wiener medizinische Wochenschrift (1946) · 2007Article
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Abstract
unlabelledTHE OBJECTIVE OF THE STUDY: We aimed to prove that the relative risk of fractures (RR) is higher in women whose T- and Z-score values come under the category of increased risk than in the women whose T-score only falls within the category of increased risk. PATIENTS AND
methodsWe analysed 498 (n=498) densitometric findings from the area of proximal femur: neck (ROI1), Ward's area (ROI2), great trochanter (ROI3) (DXA-dual energy X-ray absorptiometry, Osteocore II, France) from a population of Bratislava women of an average age of 59.71 years <58.63; 60.80>. Measured values of T- and Z-score were categorized as follows: 1--increased fracture risk (T-score<-2.5 SD/T=1, Z-score<or=-1.0 SD/Z=1), 0-without increased fracture risk (T-score>-2.5 SD/T=0, Z-score>-1.0 SD/Z=0).
resultsRR for development of fracture was higher for all measurement sites (ROI(1)-29.87; ROI(2)-15.3; ROI(3)-5.5) for women having T-score<-2.5 SD and simultaneously Z-score<or=-1.0 SD than for the women having T-score<-2.5 SD and simultaneously Z-score>-1.0 SD. When the women were divided according to age into two groups, it was found that the RR of fracture for women<65 years having a T-score<-2.5 SD and also a Z-score<or=-1.0 SD is very high (RR=infinity), elderly women (>or=65 years) had a RR for ROI(1)-32.61, for ROI(2)-7.72, and for ROI(3)-6.9. The probability (P) of the presence of women with T-score values<-2.5 SD and Z-score<or=-1.0 SD in the group under 65 years for ROI1 was 12.5%; for ROI2 34.4%; for ROI3 20.5%, and the probability for women>or=65 years was for ROI1 75%; ROI2 98% and for ROI3 100%.
conclusionsThe study's contribution lies in the finding that the relative fracture risk of the proximal femur in women increases if the T-score is <-2.5 SD and, simultaneously, the Z-score<or=-1.0 SD, this risk is especially high for women under the age of 65. In assessing the individual fracture risk in female patients we recommend to add also Z-score values in the measured area to T-score values and to other anamnestic and biochemical risk factors.
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