Evidence map›Paper›PMID 18204890›Full record

ArticleJournal of fluorescence2008

Diffusion of myelin oligodendrocyte glycoprotein in living OLN-93 cells investigated by raster-scanning image correlation spectroscopy (RICS).

Ellen Gielen, Nick Smisdom, Ben De Clercq, Martin Vandeven, Rik Gijsbers, Zeger Debyser, Jean-Michel Rigo, Johan Hofkens, Yves Engelborghs, Marcel Ameloot

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Oligodendroglial membrane dynamics in relation to myelin biogenesis.Cellular and molecular life sciences : CMLS · 2016
    Review
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Ellen GielenLaboratory for Biomolecular Dynamics, Catholic University Leuven, Celestijnenlaan 200G, 3001, Heverlee, Belgium.
Nick Smisdom
Ben De Clercq
Martin Vandeven
Rik Gijsbers
Zeger Debyser
Jean-Michel Rigo
Johan Hofkens
Yves Engelborghs
Marcel Ameloot
Hasselt University · BECatholic University of America · USKU Leuven · BEEindhoven University of Technology · NLTransnational University Limburg · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many membrane proteins and lipids are partially confined in substructures ranging from tens of nanometers to micrometers in size. Evidence for heterogeneities in the membrane of oligodendrocytes, i.e. the myelin-producing cells of the central nervous system, is almost exclusively based on detergent methods. However, as application of detergents can alter the membrane phase behaviour, it is important to investigate membrane heterogeneities in living cells. Here, we report on the first investigations of the diffusion behavior of the myelin-specific protein MOG (myelin oligodendrocyte glycoprotein) in OLN-93 as studied by the recently developed RICS (raster-scanning image correlation spectroscopy) technique. We implemented RICS on a standard confocal laser-scanning microscope with one-photon excitation and analog detection. Measurements on FITC-dextran were used to evaluate the performance of the system and the data analysis procedure.

Indexed as

AnimalsCell Line, TumorDextransDiagnostic ImagingDiffusionFluorescein-5-isothiocyanateFluorescent DyesMembrane MicrodomainsMyelin-Associated GlycoproteinMyelin-Oligodendrocyte GlycoproteinMyelin ProteinsOligodendrogliaOligodendrogliomaRatsSpectrum AnalysisDextransFluorescein-5-isothiocyanateFluorescent DyesMog protein, ratMyelin-Associated GlycoproteinMyelin-Oligodendrocyte GlycoproteinMyelin Proteins

Identifiers

PMID18204890
OpenAlexW2005558785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.