ReviewJournal of mammary gland biology and neoplasia2008
Historical perspectives of prolactin and growth hormone as mammogens, lactogens and galactagogues--agog for the future!
Review in Journal of mammary gland biology and neoplasia, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- New policies on skin-to-skin contact warrant an oxytocin-based perspective on perinatal health care.Frontiers in psychology · 2024Article
- Insulin regulates human mammosphere development and function.Cell and tissue research · 2021Article
- Pituitary Actions of EGF on Gonadotropins, Growth Hormone, Prolactin and Somatolactins in Grass Carp.Biology · 2020Article
- Hyperprolactinaemia.Journal of clinical medicine · 2019Review
- Upregulation of GH, but not IGF1, in the hippocampus of the lactating dam after kainic acid injury.Endocrine connections · 2018Article
- The Role of Placental Hormones in Mediating Maternal Adaptations to Support Pregnancy and Lactation.Frontiers in physiology · 2018Review
- Loss of vitamin D receptor signaling from the mammary epithelium or adipose tissue alters pubertal glandular development.American journal of physiology. Endocrinology and metabolism · 2014Article
- Three-dimensional organotypic culture: experimental models of mammalian biology and disease.Nature reviews. Molecular cell biology · 2014Review
- Cellular foundations of mammary tubulogenesis.Seminars in cell & developmental biology · 2014Review
- Growth hormone and reproduction: a review of endocrine and autocrine/paracrine interactions.International journal of endocrinology · 2014Review
- Characterization of Δ7/11, a functional prolactin-binding protein.Journal of molecular endocrinology · 2013Article
- Prolactin-mediated regulation of lipid biosynthesis genes in vivo in the lactating mammary epithelial cell.American journal of physiology. Endocrinology and metabolism · 2011Article
- Hormone action in the mammary gland.Cold Spring Harbor perspectives in biology · 2010Review
- Extrapituitary growth hormone.Endocrine · 2010Review
- Diverse and active roles for adipocytes during mammary gland growth and function.Journal of mammary gland biology and neoplasia · 2010Review
- Introduction: hormonal regulation of mammary development and milk protein gene expression at the whole animal and molecular levels.Journal of mammary gland biology and neoplasia · 2009Article
- Complex prolactin crosstalk in breast cancer: new therapeutic implications.Molecular and cellular endocrinology · 2009Article
- Mammary gland development.Wiley interdisciplinary reviews. Developmental biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Around 80 years ago researchers first established that the pituitary gland regulates mammary gland function as demonstrated by the ability of its extracts to promote both mammogenesis and lactogenesis in animal models. Little did they realize that in fact two hormones, prolactin (PRL) and growth hormone (GH), were contributing to these effects. By the mid 1930s PRL had been purified as a distinct lactogen, while the galactopoietic effect of GH was confirmed after its purification in the 1940s. Interest in these hormones initially centered about their potential for increasing milk production, while in the latter half of the twentieth century it became obvious that these hormones also had the potential to influence mammary cancer development. During the past 50 years large strides have been made into understanding how these hormones signal to, and within, cells of the mammary gland, paralleling rapid developments in the fields of cellular and molecular biology. In compiling this review we have summarized the progress that has been made to date regarding roles for these hormones in the mammary gland, with a goal of ensuring that some of the seminal literature is not diluted or forgotten. In doing so it is clear that there are lessons to be learned from past experiences, where new methods and technologies will continue to present exciting new opportunities to revisit lingering questions regarding these fascinating hormones and this fascinating organ.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.