ArticleJournal of neurology2008
Testing the SF-36 in Parkinson's disease. Implications for reporting rating scale data.
Article in Journal of neurology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Quality of life measures in Parkinson's disease: a systematic literature review of patient-reported outcomes measures (PROMs) and their psychometric properties.Journal of neurology · 2025Pooled it
- Differences Between Exergaming Rehabilitation and Conventional Physiotherapy on Quality of Life in Parkinson's Disease: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2021Pooled it
- Trial
- Psychometric properties of the Turkish version of the Parkinson's disease quality of life-7 (PDQoL-7) in older adults.BMC geriatrics · 2026Article
- Quality of life in patients with progressive supranuclear palsy: a review of literature and implications for practice.Frontiers in neurology · 2024Review
- Article
- The stigma of patients with chronic insomnia: a clinical study.BMC psychiatry · 2022Article
- The impact of poor medication knowledge on health-related quality of life in people with Parkinson's disease: a mediation analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Psychometric properties of the WHOQOL-BREF among next of kin to older persons in nursing homes.Health and quality of life outcomes · 2020Article
- Validation of an Individualized Measure of Quality of Life, Patient Generated Index, for Use with People with Parkinson's Disease.Neurology research international · 2020Article
- Economic evaluation of deep-brain stimulation for Tourette's syndrome: an initial exploration.Journal of neurology · 2019Article
- Cognitive behavioral therapy for depression in Japanese Parkinson's disease patients: a pilot study.Neuropsychiatric disease and treatment · 2016Article
- Psychometric performance of a generic walking scale (Walk-12G) in multiple sclerosis and Parkinson's disease.Journal of neurology · 2012Article
- Walking ability is a major contributor to fear of falling in people with Parkinson's disease: implications for rehabilitation.Parkinson's disease · 2012Article
- A scientific approach to optimal treatment of cruciate ligament injuries.Acta orthopaedica · 2011Article
- A mind-body approach for precompetitive anxiety in power-lifters: 2 case studies.Journal of chiropractic medicine · 2010Article
- Uncovering indicators of the international classification of functioning, disability, and health from the 39-item Parkinson's disease questionnaire.Parkinson's disease · 2010Article
- Interpretation of response categories in patient-reported rating scales: a controlled study among people with Parkinson's disease.Health and quality of life outcomes · 2010Article
- Responsiveness of the Harris Hip Score and the SF-36: five years after total hip arthroplasty.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2009Article
- Quality of life in Serbian patients with Parkinson's disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rating scales are increasingly the primary outcome measures in clinical trials. However, clinically meaningful interpretation of such outcomes requires that the scales used satisfy basic requirements (scaling assumptions) within the data. These are rarely tested. The SF-36 is the most widely used patient-reported rating scale. Its scaling assumptions have been challenged in neurological disorders but remain untested in Parkinson's disease (PD). We therefore tested these by analyzing SF-36 data from 202 PD patients (54% men; mean age 70) to determine if it was legitimate to report scores for the eight SF-36 scales and its two summary measures of physical and mental health, and if those scores were reliable and valid. Results supported generation of the eight SF-36 scale scores and their reliabilities were generally good (> or = 0.74 in all but one instance). However, we found limitations that question the meaningfulness of four scales and other limitations that restrict the ability of four scales to detect change in clinical trials (floor/ceiling effects, 19.6-46.2 %). The two SF-36 summary measures were not found to be valid indicators of physical and mental health. This study demonstrates important limitations of the SF-36 and provides the first evidence-based guidelines for its use in PD. The limitations of the SF-36 demonstrated here may explain some unexpected findings in previous studies. However, the main implication is a general one for the clinical research community regarding requirements for reporting rating scale endpoints. Specifically, investigators should routinely provide scale evaluations based on data from within major clinical trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.