ReviewClinical microbiology reviews2008
Infections caused by Scedosporium spp.
Review in Clinical microbiology reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 279 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
279 citing papers in PubMed, 2 syntheses or guidelines pooled it, 747 citations in OpenAlex.
- Restoring nature with microbes: bioremediation in the world's biodiversity hotspots.Applied and environmental microbiology · 2025Pooled it
- Scedosporium spp lung infection in immunocompetent patients: A systematic review and MOOSE-compliant meta-analysis.Medicine · 2019Pooled it
- From misdiagnosis to precision management: Thoracic vertebral infection caused byMedical mycology case reports · 2026Article
- Early inflammatory macrophage reprogramming byVirulence · 2026Article
- Article
- A complicated case of a spinal Scedosporium apiospermum infection with a favorable outcome-case report.Wiener medizinische Wochenschrift (1946) · 2026Article
- Endocarditis Due toOpen forum infectious diseases · 2026Article
- A hospital-based retrospective study of hospitalizations with hyalohyphomycosis and phaeohyphomycosis in the United States.Lancet regional health. Americas · 2026Article
- Destructive Mold Osteomyelitis of the Wrist Caused byJournal of clinical medicine · 2026Article
- Molecular screening for Rickettsia, Anaplasma, and Coxiella in head lice (Pediculus humanus capitis) collected from primary school girls in Fars Province, Iran (2024).BMC research notes · 2026Article
- Pulmonary fungus ball due to Scedosporium apiospermum mimicking aspergilloma: a case report.Infection · 2026Article
- Review
- Scedosporium apiospermum endocarditis in an immunocompetent patient: a case report and literature review.Journal of cardiothoracic surgery · 2026Review
- DisseminatedBMJ case reports · 2026Article
- A review on clinical cases of rare mold infections and their antifungal treatment strategies.Frontiers in microbiology · 2026Review
- Pulmonary mycoses: a clinical perspective.Breathe (Sheffield, England) · 2026Review
- Implications of gut microbiota-mediated epigenetic modifications in intestinal diseases.Gut microbes · 2025Review
- The contribution of mycetoma grains to suboptimal disease management.Nature communications · 2025Review
- In vitro evaluation of olorofim and antifungal combinations against Aspergillus and Candida species.The Journal of antimicrobial chemotherapy · 2025Article
- Non-JHLT open · 2025Review
219 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 5 institutions in 2 countries.
Funding
Abstract
Scedosporium spp. are increasingly recognized as causes of resistant life-threatening infections in immunocompromised patients. Scedosporium spp. also cause a wide spectrum of conditions, including mycetoma, saprobic involvement and colonization of the airways, sinopulmonary infections, extrapulmonary localized infections, and disseminated infections. Invasive scedosporium infections are also associated with central nervous infection following near-drowning accidents. The most common sites of infection are the lungs, sinuses, bones, joints, eyes, and brain. Scedosporium apiospermum and Scedosporium prolificans are the two principal medically important species of this genus. Pseudallescheria boydii, the teleomorph of S. apiospermum, is recognized by the presence of cleistothecia. Recent advances in molecular taxonomy have advanced the understanding of the genus Scedosporium and have demonstrated a wider range of species than heretofore recognized. Studies of the pathogenesis of and immune response to Scedosporium spp. underscore the importance of innate host defenses in protection against these organisms. Microbiological diagnosis of Scedosporium spp. currently depends upon culture and morphological characterization. Molecular tools for clinical microbiological detection of Scedosporium spp. are currently investigational. Infections caused by S. apiospermum and P. boydii in patients and animals may respond to antifungal triazoles. By comparison, infections caused by S. prolificans seldom respond to medical therapy alone. Surgery and reversal of immunosuppression may be the only effective therapeutic options for infections caused by S. prolificans.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.