Evidence map›Paper›PMID 18202396›Full record

ArticleGenetics2008

Investigations of CHD1 function in transcription and development of Drosophila melanogaster.

Ivy E McDaniel, Jennifer M Lee, Matthew S Berger, Cori K Hanagami, Jennifer A Armstrong

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

  1. Temporal and Cell-Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Epigenetics and Early Development.Journal of developmental biology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ivy E McDanielJoint Science Department, W. M. Keck Science Center, Scripps, Claremont McKenna, and Pitzer Colleges, Claremont, California 91711, USA.
Jennifer M Lee
Matthew S Berger
Cori K Hanagami
Jennifer A Armstrong
Scripps College · USPitzer College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this report we describe chd1 mutant alleles and show that the CHD1 chromatin-remodeling factor is important for wing development and fertility. While CHD1 colocalizes with elongating RNA polymerase II (Pol II) on polytene chromosomes, elongating Pol II can persist on chromatin in the absence of CHD1. These results clarify the roles of chromatin remodelers in transcription and provide novel insights into CHD1 function.

Indexed as

Transcription, GeneticAllelesAnimalsChromosomesDNA-Binding ProteinsDNA HelicasesDrosophila melanogasterDrosophila ProteinsFemaleFertilityGenes, EssentialHomeodomain ProteinsMaleMutationOogenesisProtein BindingCHD1 protein, DrosophilaDNA-Binding ProteinsDNA HelicasesDrosophila ProteinsHomeodomain Proteinskis protein, DrosophilaTranscription Factors

Identifiers

PMID18202396
PMCPMC2206105
OpenAlexW2108232273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.