ReviewAnnals of the Royal College of Surgeons of England2007
The integrative physiology of the bladder.
Review in Annals of the Royal College of Surgeons of England, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 51 citations in OpenAlex.
- Urinary catheters: state of the art and future perspectives - a narrative review.Materials today. Bio · 2025Review
- Effect of Older Age on Postoperative Urinary Retention After Prolapse Surgery.Urogynecology (Philadelphia, Pa.) · 2025Article
- Article
- Bladder biomechanics and the use of scaffolds for regenerative medicine in the urinary bladder.Nature reviews. Urology · 2018Review
- Definition and symptoms of underactive bladder.Investigative and clinical urology · 2017Review
- Prostaglandin E2 excitatory effects on rat urinary bladder: a comparison between the β-adrenoceptor modulation of non-voiding activity in vivo and micro-contractile activity in vitro.Naunyn-Schmiedeberg's archives of pharmacology · 2015Article
- Neurogenic mechanisms in bladder and bowel ageing.Biogerontology · 2015Review
- Voiding dysfunction due to detrusor underactivity: an overview.Nature reviews. Urology · 2014Review
- Overactive bladder syndrome and the potential role of prostaglandins and phosphodiesterases: an introduction.Nephro-urology monthly · 2013Review
- Management of overactive bladder.Nature reviews. Urology · 2010Review
- The overactive bladder.Therapeutic advances in urology · 2010Article
- A new look at detrusor underactivity: impaired contractility versus afferent dysfunction.Current urology reports · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Normal bladder function is complex, resulting from the co-operative interaction of numerous regulatory cell types, of which the interstitial cells and the peripheral neurones are particularly interesting. Collectively, these comprise the myovesical plexus, which appears to confer structural and functional characteristics on the bladder loosely akin to those of the gut. These include functional modularity, which gives rise to the potential for localised and propagating peristalsis-like movements in the bladder wall according to the prevailing physiological conditions. Localised modular activity during filling may contribute to normal generation of sensation and exaggerated modular activity may give rise to urinary urgency. Enhanced co-ordination of modular activity occurs in various models of detrusor overactivity; it leads to surges of contraction over a large part of the bladder wall, generating phasic changes in intravesical pressure. During voiding, the myovesical plexus sustains detrusor contraction at the behest of the brainstem, monitoring state of bladder fullness as it does so, as a guide to the required duration for which it has to keep up the effort. Accordingly, the bladder wall itself may house structures which render the bladder the effector level in a hierarchy of lower urinary tract regulation. Dysfunction in these vital regulatory structures is an underestimated factor in the pathophysiology of clinical bladder problems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.