ArticlePLoS medicine2008
Can the new humanized mouse model give HIV research a boost.
Article in PLoS medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- CD4+CD8+ T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection.Journal of immunology (Baltimore, Md. : 1950) · 2012Trial
- Comparative pathogenesis of Ebola virus and Reston virus infection in humanized mice.JCI insight · 2019Article
- Ebola virus disease in mice with transplanted human hematopoietic stem cells.Journal of virology · 2015Article
- Morphine enhances HIV-1SF162-mediated neuron death and delays recovery of injured neurites.PloS one · 2014Article
- Physiologic changes in a nonhuman primate model of HIV-associated pulmonary arterial hypertension.American journal of respiratory cell and molecular biology · 2013Article
- Expansion of activated memory CD4+ T cells affects infectivity of CCR5-tropic HIV-1 in humanized NOD/SCID/JAK3null mice.PloS one · 2013Article
- Animal models for microbicide studies.Current HIV research · 2012Review
- Characteristics of Borrelia hermsii infection in human hematopoietic stem cell-engrafted mice mirror those of human relapsing fever.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Pulmonary vascular lesions are common in SIV- and SHIV-env-infected macaques.AIDS research and human retroviruses · 2011Article
- Emerging nanotechnology approaches for HIV/AIDS treatment and prevention.Nanomedicine (London, England) · 2010Review
- Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice.Journal of virology · 2009Article
- Microbicide safety/efficacy studies in animals: macaques and small animal models.Current opinion in HIV and AIDS · 2008Article
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Abstract
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.