ReviewRespiratory research2008
Recent advances in asthma genetics.
Review in Respiratory research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled-analysis of the association between TIM-1 5383_5397 insertion/deletion polymorphism and asthma susceptibility.Molecular biology reports · 2014Pooled it
- Pooled it
- Pooled genome-wide analysis to identify novel risk loci for pediatric allergic asthma.PloS one · 2011Pooled it
- Explainable artificial intelligence-driven ensemble learning for asthma risk prediction using machine and deep learning.The Journal of international medical research · 2026Article
- Insights Into Effects of Natural Bioactive Components on Inflammatory Diseases in Respiratory Tract.Phytotherapy research : PTR · 2025Review
- Explore the Effect of Asthma Regulating HIF-1 Pathway on Sperm Quality Based on Rat Model.BioMed research international · 2022Article
- Study on the Mechanism of Jiawei Shengjiang Powder in Improving Male Asthma-Induced Asthenospermia Based on Network Pharmacology and Bioinformatics.Drug design, development and therapy · 2021Article
- Association of Interleukin-12A rs568408 with Susceptibility to Asthma in Taiwan.Scientific reports · 2017Article
- Article
- The role of Sema4A in angiogenesis, immune responses, carcinogenesis, and retinal systems.Cell adhesion & migration · 2016Review
- IgE-Related Chronic Diseases and Anti-IgE-Based Treatments.Journal of immunology research · 2016Review
- Article
- Asthma risk factors.International forum of allergy & rhinology · 2015Review
- Copy number variation burden on asthma subgenome in normal cohorts identifies susceptibility markers.Allergy, asthma & immunology research · 2015Article
- Article
- Mapping asthma-associated variants in admixed populations.Frontiers in genetics · 2015Review
- Gene susceptibility in Iranian asthmatic patients: a narrative review.Annals of medical and health sciences research · 2014Review
- Development of a High-resolution Melting Analysis Method Based on SYBR Green-I for rs7216389 Locus Genotyping in Asthmatic Child Patients.Avicenna journal of medical biotechnology · 2014Article
- The potential for genetically altered microglia to influence glioma treatment.CNS & neurological disorders drug targets · 2013Review
- Genetic polymorphisms and associated susceptibility to asthma.International journal of general medicine · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are over 100 genes that have been reported to be associated with asthma or related phenotypes. In 2006-2007 alone there were 53 novel candidate gene associations reported in the literature. Replication of genetic associations and demonstration of a functional mechanism for the associated variants are needed to confirm an asthma susceptibility gene. For most of the candidate genes there is little functional information. In a previous review by Hoffjan et al. published in 2003, functional information was reported for 40 polymorphisms and here we list another 22 genes which have such data. Some important genes such as filaggrin, interleukin-13, interleukin-17 and the cysteinyl leukotriene receptor-1 which not only were replicated by independent association studies but also have functional data are reviewed in this article.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.