ArticleInternational journal of experimental pathology2008
Protein metabolism in slow- and fast-twitch skeletal muscle during turpentine-induced inflammation.
Article in International journal of experimental pathology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 37 citations in OpenAlex.
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- Eicosapentaenoic acid enhances skeletal muscle hypertrophy without altering the protein anabolic signaling pathway.Physiological research · 2021Article
- Ixazomib, an oral proteasome inhibitor, exhibits potential effect in dystrophin-deficient mdx mice.International journal of experimental pathology · 2021Article
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- Effects of low and high doses of fenofibrate on protein, amino acid, and energy metabolism in rat.International journal of experimental pathology · 2020Article
- Effects of histidine supplementation on amino acid metabolism in rats.Physiological research · 2020Article
- Beta-hydroxy-beta-methylbutyrate supplementation and skeletal muscle in healthy and muscle-wasting conditions.Journal of cachexia, sarcopenia and muscle · 2017Review
- Acute effects of phenylbutyrate on glutamine, branched-chain amino acid and protein metabolism in skeletal muscles of rats.International journal of experimental pathology · 2017Article
- Marginal dietary zinc deprivation augments sepsis-induced alterations in skeletal muscle TNF-α but not protein synthesis.Physiological reports · 2016Article
- Alterations in protein and amino acid metabolism in rats fed a branched-chain amino acid- or leucine-enriched diet during postprandial and postabsorptive states.Nutrition & metabolism · 2016Article
- Gestational hypermethioninaemia alters oxidative/nitrative status in skeletal muscle and biomarkers of muscular injury and inflammation in serum of rat offspring.International journal of experimental pathology · 2015Article
- Breed, sex and anatomical location-specific gene expression profiling of the porcine skeletal muscles.BMC genetics · 2013Article
- The dose-dependent effects of endotoxin on protein metabolism in two types of rat skeletal muscle.Journal of physiology and biochemistry · 2012Article
- Muscle wasting in animal models of severe illness.International journal of experimental pathology · 2012Review
- Effects of β-hydroxy-β-methylbutyrate treatment in different types of skeletal muscle of intact and septic rats.Journal of physiology and biochemistry · 2010Article
- Upregulation of MHC class I in transgenic mice results in reduced force-generating capacity in slow-twitch muscle.Muscle & nerve · 2009Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of our study was to evaluate the differences in protein and amino acid metabolism after subcutaneous turpentine administration in the soleus muscle (SOL), predominantly composed of red fibres, and the extensor digitorum longus muscle (EDL) composed of white fibres. Young rats (40-60 g) were injected subcutaneously with 0.2 ml of turpentine oil/100 g body weight (inflammation) or with the same volume of saline solution (control). Twenty-four hours later SOL and EDL were dissected and incubated in modified Krebs-Heinseleit buffer to estimate total and myofibrillar proteolysis, chymotrypsin-like activity of proteasome (CHTLA), leucine oxidation, protein synthesis and amino acid release into the medium. The data obtained demonstrate that in intact rats, all parameters measured except protein synthesis are significantly higher in SOL than in EDL. In turpentine treated animals, CHTLA increased and protein synthesis decreased significantly more in EDL. Release of leucine was inhibited significantly more in SOL. We conclude that turpentine-induced inflammation affects more CHTLA, protein synthesis and leucine release in EDL compared to SOL.
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