Evidence map›Paper›PMID 18195185›Full record

ReviewCirculation2008

Aortic aneurysms: an immune disease with a strong genetic component.

Helena Kuivaniemi, Chris D Platsoucas, M David Tilson

Abstract readReview
In one paragraph

Review in Circulation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Abdominal aortic aneurysm progression: A review of preclinical and clinical data.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Review
  6. Article
  7. Review
  8. Causal associations between 17 common autoimmune diseases and aortic diseases: a Mendelian randomization study.International journal of cardiology. Cardiovascular risk and prevention · 2025
    Article
  9. Article
  10. Article
  11. The role of miR-155 in cardiovascular diseases: Potential diagnostic and therapeutic targets.International journal of cardiology. Cardiovascular risk and prevention · 2025
    Review
  12. Article
  13. Article
  14. Bioengineered vascular grafts with a pathogenicScience translational medicine · 2024
    Article
  15. Article
  16. Article
  17. Status of diagnosis and therapy of abdominal aortic aneurysms.Frontiers in cardiovascular medicine · 2023
    Review
  18. Article
  19. Review
  20. Article

28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Helena KuivaniemiCenter for Molecular Medicine and Genetics and Department of Surgery, Wayne State University School of Medicine, 540 E Canfield Ave, Detroit, MI 48201, USA. kuivan@sanger.med.wayne.edu
Chris D Platsoucas
M David Tilson

Funding

GENETIC FACTORS IN ABDOMINAL AORTIC ANEURYSMSR01HL064310 · NHLBI · WAYNE STATE UNIVERSITY · PI KUIVANIEMI, S HELENA · 1999 to 2006
$2.5M
IS AAA AN ANTIGEN-DRIVEN AUTOIMMUNE DISEASE? 'COLLABORATR01HL064340 · NHLBI · TEMPLE UNIVERSITY · PI PLATSOUCAS, CHRIS D · 1999 to 2002
$1.0M
AUTOIMMUNE AORTIC ANTIGENS IN ABDOMINAL AORTIC ANEURYSMSR01HL064334 · NHLBI · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI TILSON, MARTIN D. · 1999 to 2002
$776k
MOLECULAR BIOLOGY OF AORTIC ANEURYSMSR01HL045996 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI KUIVANIEMI, S HELENA · 1991 to 1994
–
NHLBI NIH HHS HL064310NHLBI NIH HHS HL064334NHLBI NIH HHS HL064340NHLBI NIH HHS R01 HL045996NHLBI NIH HHS R01 HL064310NHLBI NIH HHS R01 HL064334NHLBI NIH HHS R01 HL064340
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Aortic AneurysmGenetic Predisposition to DiseaseHumansImmune System DiseasesRisk FactorsSyndrome

Identifiers

PMID18195185
PMCPMC3001294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.