Evidence map›Paper›PMID 18195055›Full record

ArticleAntimicrobial agents and chemotherapy2008

Microdialysis study of imipenem distribution in the peritoneal fluid of rats with experimental acute pancreatitis.

Sandrine Lefeuvre, Sandrine Marchand, Claudine Pariat, Isabelle Lamarche, William Couet

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sandrine LefeuvreINSERM, ERI-23, Pôle Biologie Santé, 40 Avenue du Recteur, 86000 Poitiers, France.
Sandrine Marchand
Claudine Pariat
Isabelle Lamarche
William Couet
Centre Hospitalier Universitaire de Poitiers · FRInserm · FRUniversité de Poitiers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imipenem distribution was characterized by microdialysis in the peritoneal fluid of rats with experimental pancreatitis. The ratios of peritoneal fluid to blood area under unbound concentration-versus-time curves were close to unity, suggesting that imipenem was not degraded in peritoneal fluid.

Indexed as

MicrodialysisAcute DiseaseAnimalsAnti-Bacterial AgentsArea Under CurveAscitic FluidImipenemInjections, IntravenousMalePancreatitisRatsRats, Sprague-DawleyAnti-Bacterial AgentsImipenem

Identifiers

PMID18195055
PMCPMC2292542
OpenAlexW2047598269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.