ReviewCNS drugs2008
Office-based maintenance treatment of opioid dependence: how does it compare with traditional approaches?
Review in CNS drugs, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 48 citations in OpenAlex.
- Unobserved versus observed office buprenorphine/naloxone induction: a pilot randomized clinical trial.Addictive behaviors · 2010Trial
- Efficacy of Buprenorphine/Naloxone Rapidly Dissolving Sublingual Tablets (BNX-RDT) After Switching From BNX Sublingual Film.Journal of addiction medicineTrial
- Knowledge, attitudes, and practices in obesity among trained and in-training primary care providers in an urban safety-net hospital system.Obesity pillars · 2025Article
- Article
- A cascade of care for alcohol use disorder: Using 2015-2019 National Survey on Drug Use and Health data to identify gaps in past 12-month care.Alcoholism, clinical and experimental research · 2021Article
- The Role of Behavioral Interventions in Buprenorphine Maintenance Treatment: A Review.The American journal of psychiatry · 2017Review
- Type of opioid dependence among patients seeking opioid substitution treatment: are there differences in background and severity of problems?Substance abuse treatment, prevention, and policy · 2016Article
- Use of pharmacotherapies in the treatment of alcohol use disorders and opioid dependence in primary care.BioMed research international · 2015Review
- Emerging adult age status predicts poor buprenorphine treatment retention.Journal of substance abuse treatment · 2014Article
- Benzodiazepine use during buprenorphine treatment for opioid dependence: clinical and safety outcomes.Drug and alcohol dependence · 2013Article
- A call for evidence-based medical treatment of opioid dependence in the United States and Canada.Health affairs (Project Hope) · 2013Article
- Improving public health through access to and utilization of medication assisted treatment.International journal of environmental research and public health · 2011Review
- Buprenorphine for prescription opioid addiction in a patient with depression and alcohol dependence.The American journal of psychiatry · 2011Article
- Clinical experience with fortnightly buprenorphine/naloxone versus buprenorphine in Italy: preliminary observational data in an office-based setting.Clinical drug investigation · 2010Article
- Therapeutic switch to buprenorphine/naloxone from buprenorphine alone: clinical experience in an Italian addiction centre.Clinical drug investigation · 2010Article
- High levels of opioid analgesic co-prescription among methadone maintenance treatment clients in British Columbia, Canada: results from a population-level retrospective cohort study.The American journal on addictionsArticle
- Improving temporal efficiency of outpatient buprenorphine induction.The American journal on addictionsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The increasing global public health burden of heroin dependence and prescription opioid dependence warrants further expansion of treatment models. The most effective intervention for opioid dependence remains maintenance with methadone, a full mu-opioid receptor agonist, or buprenorphine, a partial mu-opioid receptor agonist.A growing body of evidence supports the use of opioid receptor agonist maintenance in office-based settings. Office-based opioid treatment (OBOT) can expand treatment access in a less stigmatized environment, which enables integrated care of co-morbid conditions. The current review primarily examines OBOT in the US, although a comparison with the British and French models is provided, given that the public health impact and implementation of OBOT will likely vary between countries because of policy and logistical differences. The comparative effectiveness of maintenance treatment in office-based and traditional programme-based models of care requires further study. Clinical and practical considerations when providing treatment for opioid dependence in traditional versus office-based settings include patient selection and monitoring, health economics, management of co-morbid conditions, and access to ancillary psychosocial treatment. OBOT is not a replacement for more structured, traditional models of care, but provides an additional opportunity to help address the tremendous public health impact of opioid dependence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.