Evidence map›Paper›PMID 18193446›Full record

ReviewChromosoma2008

Telomere capping in Drosophila: dealing with chromosome ends that most resemble DNA breaks.

Yikang S Rong

Abstract readReview
PubMed Publisher
In one paragraph

Review in Chromosoma, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
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  5. Review
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  15. Untangling the web: the diverse functions of the PIWI/piRNA pathway.Molecular reproduction and development · 2013
    Review
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Yikang S RongLaboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA. rongy@mail.nih.gov

Funding

DNA Double Strand Break Repair in Drosophila MelanogasterZIABC010446 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI RONG, YIKANG · 2009 to 2015
$6.9M
DNA Double Strand Break Repair in Drosophila MelanogasterZ01BC010446 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI RONG, YIKANG · 2002 to 2008
$1.9M
Intramural NIH HHS
6 · The paper itself

Abstract

Telomere caps prevent chromosome ends from being recognized as DNA double-strand breaks (DSBs). Unlike most organisms studied, the telomere-capping function of Drosophila does not require a specific sequence. Without this sequence component, Drosophila telomeres most resemble DNA breaks and, thus, represent a simpler system for the study of telomere capping. I review recent progress in Drosophila telomere studies, and challenge the notion that Drosophila may not be a relevant model for the study of telomere maintenance.

Indexed as

DNA BreaksAnimalsChromosomesDrosophila melanogasterDrosophila ProteinsEvolution, MolecularTelomereDrosophila Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.