ReviewImmunologic research2008
Understanding the multiple functions of Gr-1(+) cell subpopulations during microbial infection.
Review in Immunologic research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- Inhibition of Bruton's tyrosine kinase restricts neuroinflammation following intracerebral hemorrhage.Theranostics · 2025Article
- Intranasally Inoculated SARS-CoV-2 Spike Protein Combined with Mucoadhesive Polymer Induces Broad and Long-Lasting Immunity.Vaccines · 2024Article
- Multi-Omics Profiling Reveals Phenotypic and Functional Heterogeneity of Neutrophils in COVID-19.International journal of molecular sciences · 2024Article
- Ly6CCell reports · 2024Article
- Article
- Neutrophil inhibition improves acute inflammation in a murine model of viral myocarditis.Cardiovascular research · 2023Article
- Neutrophil subsets and their differential roles in viral respiratory diseases.Journal of leukocyte biology · 2022Review
- Eosinophils and Neutrophils Eliminate MigratingFrontiers in immunology · 2021Article
- Gr-1+ Cells Other Than Ly6G+ Neutrophils Limit Virus Replication and Promote Myocardial Inflammation and Fibrosis Following Coxsackievirus B3 Infection of Mice.Frontiers in cellular and infection microbiology · 2018Article
- Repetitive Exposure of IL-17 Into the Murine Air Pouch Favors the Recruitment of Inflammatory Monocytes and the Release of IL-16 and TREM-1 in the Inflammatory Fluids.Frontiers in immunology · 2018Article
- The homing receptor CD44 is involved in the progression of precancerous gastric lesions in patients infected with Helicobacter pylori and in development of mucous metaplasia in mice.Cancer letters · 2016Article
- The role of Gr-1(+) cells and tumour necrosis factor-α signalling during Clostridium difficile colitis in mice.Immunology · 2015Article
- Article
- Pivotal role of IL-6 in the hyperinflammatory responses to subacute ozone in adiponectin-deficient mice.American journal of physiology. Lung cellular and molecular physiology · 2014Article
- Involvement of Gr-1 dull+ cells in the production of TNF-α and IL-17 and exacerbated systemic inflammatory response caused by lipopolysaccharide.Inflammation · 2014Article
- Differential effects of aging and sex on stroke induced inflammation across the lifespan.Experimental neurology · 2013Article
- MAP kinase phosphatase-2 plays a key role in the control of infection with Toxoplasma gondii by modulating iNOS and arginase-1 activities in mice.PLoS pathogens · 2013Article
- TLR-independent neutrophil-derived IFN-γ is important for host resistance to intracellular pathogens.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Real-time imaging of heterotypic platelet-neutrophil interactions on the activated endothelium during vascular inflammation and thrombus Formation in live mice.Journal of visualized experiments : JoVE · 2013Article
- Role of Chemokines and Trafficking of Immune Cells in Parasitic Infections.Current immunology reviews · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The murine cell surface determinant Gr-1 is expressed at high level on neutrophils. Depletion of polymorphonuclear leukocytes with anti-Gr-1(+) monoclonal antibody results in increased susceptibility and dysregulated immunity to many microbial pathogens, a finding widely interpreted to indicate the importance of neutrophils during infection. Yet, in recent years it has become clear that additional cell types express the Gr-1 determinant, including dendritic cell and monocyte subpopulations. In this review, we evaluate current knowledge on the functional aspects of Gr-1(+) cell populations. We focus on infection with the opportunistic protozoan Toxoplasma gondii, a case where host survival depends on an intact Gr-1(+) cell population.
Indexed as
Identifiers
18193362What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.