ArticleBiophysical journal2008
Intracellular microrheology of motile Amoeba proteus.
Article in Biophysical journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 71 citations in OpenAlex.
- HAK-actin, a U-ExM-compatible probe to image the actin cytoskeleton.Cell reports methods · 2026Article
- Characterization of cellular wound resistance in the giant ciliatebioRxiv : the preprint server for biology · 2025Article
- Topological damping in an ultrafast giant cell.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- The Intracellular Amastigote of Trypanosoma cruzi Maintains an Actively Beating Flagellum.mBio · 2023Article
- Glass-like characteristics of intracellular motion in human cells.Biophysical journal · 2021Article
- Evidence of conditioned behavior in amoebae.Nature communications · 2019Article
- Cell polarity: having and making sense of direction-on the evolutionary significance of the primary cilium/centrosome organ in Metazoa.Open biology · 2018Review
- A computational model for how cells choose temporal or spatial sensing during chemotaxis.PLoS computational biology · 2018Article
- Integrated Analysis of Intracellular Dynamics of MenaINV Cancer Cells in a 3D Matrix.Biophysical journal · 2017Article
- Cytoskeletal architecture and its evolutionary significance in amoeboid eukaryotes and their mode of locomotion.Royal Society open science · 2016Article
- Impact of dimensionality and network disruption on microrheology of cancer cells in 3D environments.PLoS computational biology · 2014Article
- Decoupling directed and passive motion in dynamic systems: particle tracking microrheology of sputum.Annals of biomedical engineering · 2013Article
- Reconstruction of active regular motion in amoeba extract: dynamic cooperation between sol and gel states.PloS one · 2013Article
- Python algorithms in particle tracking microrheology.Chemistry Central journal · 2012Article
- Analytical tools to distinguish the effects of localization error, confinement, and medium elasticity on the velocity autocorrelation function.Biophysical journal · 2012Article
- High-throughput ballistic injection nanorheology to measure cell mechanics.Nature protocols · 2012Article
- The physics of cancer: the role of physical interactions and mechanical forces in metastasis.Nature reviews. Cancer · 2011Review
- Article
- Characterization of hydrogel microstructure using laser tweezers particle tracking and confocal reflection imaging.Journal of physics. Condensed matter : an Institute of Physics journal · 2010Article
- Multiphase flow models of biogels from crawling cells to bacterial biofilms.HFSP journal · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The motility of Amoeba proteus was examined using the technique of passive particle tracking microrheology, with the aid of newly developed particle tracking software, a fast digital camera, and an optical microscope. We tracked large numbers of endogeneous particles in the amoebae, which displayed subdiffusive motion at short timescales, corresponding to thermal motion in a viscoelastic medium, and superdiffusive motion at long timescales due to the convection of the cytoplasm. Subdiffusive motion was characterized by a rheological scaling exponent of 3/4 in the cortex, indicative of the semiflexible dynamics of the actin fibers. We observed shear-thinning in the flowing endoplasm, where exponents increased with increasing flow rate; i.e., the endoplasm became more fluid-like. The rheology of the cortex is found to be isotropic, reflecting an isotropic actin gel. A clear difference was seen between cortical and endoplasmic layers in terms of both viscoelasticity and flow velocity, where the profile of the latter is close to a Poiseuille flow for a Newtonian fluid.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.