ReviewHormones and behavior2008
The spinal nucleus of the bulbocavernosus: firsts in androgen-dependent neural sex differences.
Review in Hormones and behavior, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 104 citations in OpenAlex.
- Sry-modified laboratory rat lines to study sex-chromosome effects underlying sex differences in physiology and disease: Four Core Genotypes and more.Biology of sex differences · 2026Article
- A 3D Atlas of Visceral and Somatic Pelvic Motor Neurons in Whole Mounts of Female and Male Rat Spinal Cords.The Journal of comparative neurology · 2025Article
- Serum metabolomic analysis of lumbar disc herniation at different location based on UPLC-QTOF-MS/MS: a population study.Journal of orthopaedics · 2025Article
- Brain Nuclei in the Regulation of Sexual Behavior, Peripheral Nerves Related to Reproduction, and Their Alterations in Neurodegenerative Diseases: A Brief Review.Brain sciences · 2025Review
- Patterns of connexin36 and eGFP reporter expression among motoneurons in spinal sexually dimorphic motor nuclei in mouse.International journal of physiology, pathophysiology and pharmacology · 2024Article
- Sex Steroids as Regulators of Gestural Communication.Endocrinology · 2020Review
- Sex bias and omission in neuroscience research is influenced by research model and journal, but not reported NIH funding.Frontiers in neuroendocrinology · 2020Review
- New concepts in the study of the sexual differentiation and activation of reproductive behavior, a personal view.Frontiers in neuroendocrinology · 2019Review
- Effects of sex and prenatal androgen manipulations on Onuf's nucleus of rhesus macaques.Hormones and behavior · 2018Article
- Genes linked to species diversity in a sexually dimorphic communication signal in electric fish.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2018Article
- Androgen receptors and muscle: a key mechanism underlying life history trade-offs.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2018Review
- Sex differences in neuromuscular androgen receptor expression and sociosexual behavior in a sex changing fish.PloS one · 2017Article
- Characterization of dendritic morphology and neurotransmitter phenotype of thoracic descending propriospinal neurons after complete spinal cord transection and GDNF treatment.Experimental neurology · 2016Article
- Postnatal development of the gastrin-releasing peptide system in the lumbosacral spinal cord controlling male reproductive function in rats.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2016Article
- Cellular and molecular mechanisms of sexual differentiation in the mammalian nervous system.Frontiers in neuroendocrinology · 2016Review
- Perinatal testosterone exposure is critical for the development of the male-specific sexually dimorphic gastrin-releasing peptide system in the lumbosacral spinal cord that mediates erection and ejaculation.Biology of sex differences · 2016Article
- Sex differences in the brain: a whole body perspective.Biology of sex differences · 2015Review
- Connexin36 in gap junctions forming electrical synapses between motoneurons in sexually dimorphic motor nuclei in spinal cord of rat and mouse.The European journal of neuroscience · 2014Article
- Sexually dimorphic nuclei in the spinal cord control male sexual functions.Frontiers in neuroscience · 2014Review
- Sensitive periods for hormonal programming of the brain.Current topics in behavioral neurosciences · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Cell number in the spinal nucleus of the bulbocavernosus (SNB) of rats was the first neural sex difference shown to differentiate under the control of androgens, acting via classical intracellular androgen receptors. SNB motoneurons reside in the lumbar spinal cord and innervate striated muscles involved in copulation, including the bulbocavernosus (BC) and levator ani (LA). SNB cells are much larger and more numerous in males than in females, and the BC/LA target muscles are reduced or absent in females. The relative simplicity of this neuromuscular system has allowed for considerable progress in pinpointing sites of hormone action, and identifying the cellular bases for androgenic effects. It is now clear that androgens act at virtually every level of the SNB system, in development and throughout adult life. In this review we focus on effects of androgens on developmental cell death of SNB motoneurons and BC/LA muscles; the establishment and maintenance of SNB motoneuron soma size and dendritic length; BC/LA muscle morphology and physiology; and behaviors controlled by the SNB system. We also describe new data on neurotherapeutic effects of androgens on SNB motoneurons after injury in adulthood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.