Evidence map›Paper›PMID 18188937›Full record

ArticleAdvances in experimental medicine and biology2008

Genetic supplementation of RDS alleviates a loss-of-function phenotype in C214S model of retinitis pigmentosa.

May Nour, Steven J Fliesler, Muna I Naash

Abstract read
In one paragraph

Article in Advances in experimental medicine and biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. New Insight into the Genotype-Phenotype Correlation ofInternational journal of molecular sciences · 2023
    Review
  3. Article
  4. Article
  5. Novel molecular mechanisms for Prph2-associated pattern dystrophy.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  6. Review
  7. Article
  8. Review
  9. Gene therapy for PRPH2-associated ocular disease: challenges and prospects.Cold Spring Harbor perspectives in medicine · 2014
    Review
  10. Article
  11. Article
  12. Article
  13. Nanoparticles for retinal gene therapy.Progress in retinal and eye research · 2010
    Review
  14. Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2010
    Article
  15. Article
  16. Gene therapy in the Retinal Degeneration Slow model of retinitis pigmentosa.Advances in experimental medicine and biology · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

May NourCell Biology, University of Oklahoma Health Sciences Center, 940 Stanton L. Young Blvd., Oklahoma City, OK 73104, USA.
Steven J Fliesler
Muna I Naash

Funding

Supplement for: Mechanism of Photoreceptor Cell Degeneration in Animal Models of Retinal DiseasesR01EY010609 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI MUAYYAD R AL-UBAIDI, Muna I. Naash · 1995 to 2026
$11.0M
CORE--MOLECULAR BIOLOGYP30EY012190 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI ANDERSON, ROBERT E · 1999 to 2009
$5.2M
ISOPRENOID METABOLISM IN THE RETINAR01EY007361 · NEI · UNIVERSITY OF SOUTH FLORIDA · PI FLIESLER, STEVEN J. · 1988 to 2015
$4.4M
Mechanism of photoreceptor cell degeneration in animal models of retinal diseasesR56EY010609 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI NAASH, MUNA I. · 2008 to 2008
$479k
Sustained, Non-viral Ocular Therapy Using NanoparticlesR03EY016201 · NEI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI NAASH, MUNA I · 2005 to 2006
$290k
PHOTORECEPTORSR55EY010609 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI NAASH, MUNA I · 1994 to 1994
–
NEI NIH HHS EY007361NEI NIH HHS EY016201NEI NIH HHS EY 10609NEI NIH HHS EY12190NEI NIH HHS P30 EY012190NEI NIH HHS R01 EY007361NEI NIH HHS R01 EY010609NEI NIH HHS R03 EY016201NEI NIH HHS R56 EY010609
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease Models, AnimalAmino Acid SubstitutionAnimalsElectroretinographyGlutamic AcidIntermediate Filament ProteinsMembrane GlycoproteinsMiceMice, TransgenicNerve Tissue ProteinsPeripherinsPhenotypeRetinal Cone Photoreceptor CellsRetinal Rod Photoreceptor CellsRetinitis PigmentosaGlutamic AcidIntermediate Filament ProteinsMembrane GlycoproteinsNerve Tissue ProteinsPeripherinsPrph2 protein, mouse

Identifiers

PMID18188937
PMCPMC2789457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.