ArticleClinical and vaccine immunology : CVI2008
Passive transfer of maternal Mycoplasma hyopneumoniae-specific cellular immunity to piglets.
Article in Clinical and vaccine immunology : CVI, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 76 citations in OpenAlex.
- Comparison of 2 commercial single-dose Mycoplasma hyopneumoniae vaccines and porcine reproductive and respiratory syndrome virus (PRRSV) vaccines on pigs dually infected with M. hyopneumoniae and PRRSV.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2016Trial
- Genetic Strategies for Improving Pig Robustness: Reducing Antibiotic Use Through Enhanced Resilience and Disease Resistance.Animals : an open access journal from MDPI · 2025Review
- Evaluation of PCV2 vaccine immunogenicity and efficacy using ELISpot to detect virus-specific memory B cells.Porcine health management · 2025Article
- The Effect of Maternal Probiotic or Synbiotic Supplementation on Sow and Offspring Gastrointestinal Microbiota, Health, and Performance.Animals : an open access journal from MDPI · 2023Review
- Testable Candidate Immune Correlates of Protection for Porcine Reproductive and Respiratory Syndrome Virus Vaccination.Vaccines · 2023Review
- Selection of internal reference gene for normalization of reverse transcription-quantitative polymerase chain reaction analysis inFrontiers in veterinary science · 2022Article
- Transfer of Mycoplasma hyopneumoniae-specific cell mediated immunity to neonatal piglets.Veterinary research · 2021Article
- Effectiveness of two intramuscular combined vaccines for the control of Mycoplasma hyopneumoniae and porcine circovirus type 2 in growing pigs: a randomized field trial.Porcine health management · 2021Article
- Passive transfer of colostral leukocytes: A benefit/risk analysis.The Canadian veterinary journal = La revue veterinaire canadienne · 2021Review
- Effect of Different Cross-Fostering Strategies on Growth Performance, Stress Status and Immunoglobulin of Piglets.Animals : an open access journal from MDPI · 2021Article
- Maternal Autogenous Inactivated Virus Vaccination Boosts Immunity to PRRSV in Piglets.Vaccines · 2021Article
- Experimental evaluation ofCanadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2021Article
- Distribution difference of colostrum-derived B and T cells subsets in gilts and sows.PloS one · 2021Article
- Efficacy Evaluation of a Bivalent Vaccine Containing Porcine Circovirus Type 2b andFrontiers in veterinary science · 2021Article
- Effects of pre-farrowing sow vaccination againstThe Veterinary record · 2019Article
- Article
- Maternal immunity enhances Mycoplasma hyopneumoniae vaccination induced cell-mediated immune responses in piglets.BMC veterinary research · 2014Article
- Colostral antibody-mediated and cell-mediated immunity contributes to innate and antigen-specific immunity in piglets.Developmental and comparative immunology · 2014Article
- Modulation of systemic immune responses through commensal gastrointestinal microbiota.PloS one · 2013Article
- Cellular adaptive immune response against porcine circovirus type 2 in subclinically infected pigs.BMC veterinary research · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunity in the neonatal animal is primarily maternally derived, either by lymphocytes that pass into the newborn across the placenta or following colostrum ingestion. However, the effect of this passively transferred cellular maternal immunity on the newborn's immune repertoire is not clearly understood. Various studies have shown that colostral lymphocytes are activated and possess functional abilities; however, no studies have shown the transfer of colostral antigen-specific T-cell-specific responses in a newborn. In this study we examined the transfer of vaccine-induced Mycoplasma hyopneumoniae cellular immunity from immune dams to newborn piglets. Newborn piglets from vaccinated and nonvaccinated dams were assessed in two ways for cellular immune responses specific to M. hyopneumoniae: (i) delayed-type hypersensitivity (DTH) testing and (ii) in vitro lymphocyte proliferation, assayed on piglet blood lymphocytes and sow colostral lymphocytes. DTH responses to M. hyopneumoniae were detected only for offspring of vaccinated sows, whereas DTH responses to the nonspecific mitogen phytohemagglutinin were seen for all piglets. M. hyopneumoniae-specific proliferation was seen for colostral lymphocytes from vaccinated sows and for blood lymphocytes from neonatal piglets of vaccinated dams but not for blood lymphocytes from piglets of nonvaccinated sows. Functional antigen-specific T cells were transferred to offspring from vaccinated sows and participated in the neonatal immune response upon stimulation. These data have implications for defining disease intervention strategies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.