The role of 18F-FLT in cancer imaging: does it really reflect proliferation?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

1. Imaging of proliferation with 18F-FLT PET/CT versus 18F-FDG PET/CT in non-small-cell lung cancer.European journal of nuclear medicine and molecular imaging · 2010
   Trial
2. Long-term prognostic value ofCancer imaging : the official publication of the International Cancer Imaging Society · 2026
   Article
3. Assessment of glucose metabolism and cellular proliferation in multiple myeloma: a first report on combinedEJNMMI research · 2018
   Article
4. Annals of nuclear medicine · 2017
   Review
5. FLT PET-CT in evaluation of treatment response.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India · 2014
   Review
6. Novel cancer-targeting SPECT/NIRF dual-modality imaging probe (99m)Tc-PC-1007: synthesis and biological evaluation.Bioorganic & medicinal chemistry letters · 2013
   Article
7. Assessment of cellular proliferation in tumors by PET using 18F-ISO-1.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2013
   Article
8. Correlation of the Ga-68-bombesin analog Ga-68-BZH3 with receptors expression in gliomas as measured by quantitative dynamic positron emission tomography (dPET) and gene arrays.Molecular imaging and biology · 2012
   Article
9. Impact of cell-proliferation-associated gene expression on 2-deoxy-2-[(18)f]fluoro-D-glucose (FDG) kinetics as measured by dynamic positron emission tomography (dPET) in colorectal tumors.Molecular imaging and biology · 2011
   Article
10. Early detection of tumor response by FLT/microPET Imaging in a C26 murine colon carcinoma solid tumor animal model.Journal of biomedicine & biotechnology · 2011
    Article
11. Detection of gastric cancer using 18F-FLT PET: comparison with 18F-FDG PET.European journal of nuclear medicine and molecular imaging · 2009
    Article
12. Reproducibility of quantitative 18F-3'-deoxy-3'-fluorothymidine measurements using positron emission tomography.European journal of nuclear medicine and molecular imaging · 2009
    Article
13. Promises and challenges of positron emission tomography for assessment of sarcoma in daily clinical practice.Cancer imaging : the official publication of the International Cancer Imaging Society · 2008
    Review

Corrections and comments

• Comment on
  Initial evaluation of 18F-fluorothymidine (FLT) PET/CT scanning for primary pancreatic cancer.2008

Authors and funding

2 authors at 2 institutions in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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