ArticleProceedings of the National Academy of Sciences of the United States of America2008
Anomalous dynamics of cell migration.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
114 citing papers in PubMed, 343 citations in OpenAlex.
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- Methods to analyze cell migration data: fundamentals and practical guidelines.Nature methods · 2026Review
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- Substrate elasticity controls fibroblast motility on non-oxidized PDMS under weak adhesion.Biophysics and physicobiology · 2026Article
- A pipeline for cell migration analysis in live-cell imaging data from human iPSC-derived forebrain assembloids.Frontiers in cell and developmental biology · 2026Article
- Capped high-force integrin bond lifetimes and spacing-tuned binding frequency drive rapid fibroblast migration.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Subdiffusion from competition between multi-exponential friction memory and energy barriers.The European physical journal. E, Soft matter · 2025Article
- Deriving the A/B Cells Policy as a Robust Multi-Object Cell Pipeline for Time-Lapse Microscopy.International journal of molecular sciences · 2025Article
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- Anisotropic persistent random walk model simulates T-cells migration over curved landscapes.Scientific reports · 2025Article
- Non-Markovian equilibrium and non-equilibrium barrier-crossing kinetics in asymmetric double-well potentials.The European physical journal. E, Soft matter · 2025Article
- A self-assembled protein β-helix as a self-contained biofunctional motif.Nature communications · 2025Article
- Enteropathogenic Escherichia coli induces Entamoeba histolytica superdiffusion movement on fibronectin by reducing traction forces.PLoS pathogens · 2025Article
- Quasi-Diffusion Imaging: Application to Ultra-High b-Value and Time-Dependent Diffusion Images of Brain Tissue.NMR in biomedicine · 2025Article
- Correction: Microglia are essential for tissue contraction in wound closure after brain injury in zebrafish larvae.Life science alliance · 2025Article
- Microglia are essential for tissue contraction in wound closure after brain injury in zebrafish larvae.Life science alliance · 2025Article
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- Elastic interactions compete with persistent cell motility to drive durotaxis.Biophysical journal · 2024Article
54 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell movement--for example, during embryogenesis or tumor metastasis--is a complex dynamical process resulting from an intricate interplay of multiple components of the cellular migration machinery. At first sight, the paths of migrating cells resemble those of thermally driven Brownian particles. However, cell migration is an active biological process putting a characterization in terms of normal Brownian motion into question. By analyzing the trajectories of wild-type and mutated epithelial (transformed Madin-Darby canine kidney) cells, we show experimentally that anomalous dynamics characterizes cell migration. A superdiffusive increase of the mean squared displacement, non-Gaussian spatial probability distributions, and power-law decays of the velocity autocorrelations is the basis for this interpretation. Almost all results can be explained with a fractional Klein-Kramers equation allowing the quantitative classification of cell migration by a few parameters. Thereby, it discloses the influence and relative importance of individual components of the cellular migration apparatus to the behavior of the cell as a whole.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.