ReviewJournal of cellular and molecular medicine2008
Molecular mechanism of regulation of the calcium-binding protein calbindin-D9k, and its physiological role(s) in mammals: a review of current research.
Review in Journal of cellular and molecular medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 61 citations in OpenAlex.
- The Role of Intestinal Cytochrome P450s in Vitamin D Metabolism.Biomolecules · 2024Article
- Effect of feeding bioactive compounds identified from plant extracts (4-hexylresorcinol, 7-hydroxycoumarin, and gamma-octalactone) on the productivity and quality of broiler meat.Veterinary world · 2022Article
- Effects of exogenous progesterone on the expression of mineral regulatory molecules by ovine endometrium and placentomes†.Biology of reproduction · 2022Article
- Effects of progesterone and interferon tau on ovine endometrial phosphate, calcium, and vitamin D signaling†.Biology of reproduction · 2022Article
- Phosphate, Calcium, and Vitamin D: Key Regulators of Fetal and Placental Development in Mammals.Advances in experimental medicine and biology · 2022Review
- Cytosolic CaCold Spring Harbor perspectives in biology · 2020Review
- Effect of Boswellia serrata Resin Supplementation on Basic Chemical and Mineral Element Composition in the Muscles and Liver of Broiler Chickens.Biological trace element research · 2017Article
- Characterization of the Transcriptional Complexity of the Receptive and Pre-receptive Endometria of Dairy Goats.Scientific reports · 2015Article
- Down-regulation of mechanisms involved in cell transport and maintenance of mucosal integrity in pigs infected with Lawsonia intracellularis.Veterinary research · 2014Article
- Cyclosporine A induces apoptotic and autophagic cell death in rat pituitary GH3 cells.PloS one · 2014Article
- Molecular mechanism(s) of endocrine-disrupting chemicals and their potent oestrogenicity in diverse cells and tissues that express oestrogen receptors.Journal of cellular and molecular medicine · 2013Review
- TRPV6 and Calbindin-D9k-expression and localization in the bovine uterus and placenta during pregnancy.Reproductive biology and endocrinology : RB&E · 2012Article
- Biomarker genes for detecting estrogenic activity of endocrine disruptors via estrogen receptors.International journal of environmental research and public health · 2012Review
- Cytosolic Ca2+ buffers.Cold Spring Harbor perspectives in biology · 2010Review
- Transcriptional and translational expression of calbindin-D9k in the duodenum, kidney and uterus of a female canine model.Journal of veterinary science · 2010Article
- Combination treatment with progesterone and vitamin D hormone may be more effective than monotherapy for nervous system injury and disease.Frontiers in neuroendocrinology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Calbindin-D(9k) (CaBP-9k) is a cytosolic calcium-binding protein that is expressed in a variety of tissues, such as uterus, placenta, intestine, kidney, pituitary gland and bone. At present, the precise role(s) of CaBP-9k remains to be clarified. CaBP-9k-null mice are normal, which indicates that other calcium-transporter genes can compensate for the lack CaBP-9k. Uterine CaBP-9k has been shown to be involved in the regulation of myometrial activity by intracellular calcium. In the uterus and placenta, CaBP-9k expression is regulated by the sex steroid hormones oestrogen (E2) and progesterone (P4). Intestinal CaBP-9k is involved in intestinal calcium absorption, and is regulated at the transcriptional and post-transcriptional levels by 1,25-dihydroxyvitamin D3, the hormonal form of vitamin D. Thus, evidence to date suggests that CaBP-9k may be regulated in a tissue-specific manner. In this review, we will summarize current data on the molecular mechanism of regulation of CaBP-9k in mammals, including recent research data generated in our laboratories.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.