ReviewCell proliferation2008
Potential for access to embryonic-like cells from human umbilical cord blood.
Review in Cell proliferation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Isolation and characterization of neural crest-like progenitor cells in human umbilical cord blood.Regenerative therapy · 2020Article
- Human Umbilical Cord Blood Cell Transplantation in Neuroregenerative Strategies.Frontiers in pharmacology · 2017Review
- Umbilical cord blood-derived non-hematopoietic stem cells retrieved and expanded on bone marrow-derived extracellular matrix display pluripotent characteristics.Stem cell research & therapy · 2016Article
- An Overview on Human Umbilical Cord Blood Stem Cell-Based Alternative In Vitro Models for Developmental Neurotoxicity Assessment.Molecular neurobiology · 2016Review
- Neurotherapeutic effect of cord blood derived CD45+ hematopoietic cells in mice after traumatic brain injury.Journal of neurotrauma · 2014Article
- Nanofiber-expanded human umbilical cord blood-derived CD34(+) cell therapy accelerates cutaneous wound closure in NOD/SCID mice.Journal of cellular and molecular medicine · 2014Article
- Intraarterial transplantation of human umbilical cord blood mononuclear cells is more efficacious and safer compared with umbilical cord mesenchymal stromal cells in a rodent stroke model.Stem cell research & therapy · 2014Article
- Enhanced survival and neurite network formation of human umbilical cord blood neuronal progenitors in three-dimensional collagen constructs.Journal of molecular neuroscience : MN · 2013Article
- Cord blood Lin(-)CD45(-) embryonic-like stem cells are a heterogeneous population that lack self-renewal capacity.PloS one · 2013Article
- Cord blood endothelial progenitor cells as therapeutic and imaging probes.Imaging in medicine · 2012Article
- In vitro modelling of cortical neurogenesis by sequential induction of human umbilical cord blood stem cells.Stem cell reviews and reports · 2012Article
- Article
- Regenerative therapies for diabetic microangiopathy.Experimental diabetes research · 2012Review
- Immunological applications of stem cells in type 1 diabetes.Endocrine reviews · 2011Review
- The science and ethics of induced pluripotency: what will become of embryonic stem cells?Mayo Clinic proceedings · 2011Article
- The umbilical cord: a rich and ethical stem cell source to advance regenerative medicine.Cell proliferation · 2011Review
- Promising new sources for pluripotent stem cells.Stem cell reviews and reports · 2010Review
- Future of cord blood for non-oncology uses.Bone marrow transplantation · 2009Review
- Private cord blood banking: current use and clinical future.Stem cell reviews and reports · 2009Review
- Stem cell platforms for regenerative medicine.Clinical and translational science · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
All too often media attention clouds the reality that there are many types of stem cell. The embryos, bone marrow and umbilical cord blood (UCB) are the three most used sources. However, despite what it would appear, embryonic stem cells have not been the first to yield life-saving cures at present. Faster routes to clinical intervention have been using adult stem cells that can be sourced from bone marrow and from cord blood, and that are readily accessible and are more ethically acceptable to the general public. Both these non-embryonic sources have been able to provide sufficient numbers of cells to allow development of clinical translational protocols. Bone marrow-derived cells have been used successfully in myocardial infarct therapy where relining by endothelial tissue has allowed limited reperfusion to damaged cardiac tissue. UCB have also demonstrated significant success for around 20 years in haematotransplantation. With a global human population in excess of 6 billion, births thus UCB, remain the largest untouched source of stem cells available every year. UCB also provide a distinct advantage over other adult stem cells due to the length of the telomere and also due protected immunological status of the developing neonatal environment. The total mutation load in the UCB populations is clearly likely to be significant less than in adult tissues.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.