ReviewClinical reviews in allergy & immunology2008
Systemic lupus erythematosus involving the nervous system: presentation, pathogenesis, and management.
Review in Clinical reviews in allergy & immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 49 citations in OpenAlex.
- A child with recurrent headache, fever and diffuse meningeal enhancement on MRI.Clinical rheumatology · 2024Review
- Neurological and endocrinological involvement in neonatal lupus erythematosus: a retrospective study at a tertiary hospital in Eastern China.Clinical rheumatology · 2023Article
- Abnormal cortical thickness and structural covariance networks in systemic lupus erythematosus patients without major neuropsychiatric manifestations.Arthritis research & therapy · 2022Article
- Vasculitis, Autoimmunity, and Cytokines: How the Immune System Can Harm the Brain.International journal of environmental research and public health · 2021Review
- Autoantibodies associated with neuropsychiatric systemic lupus erythematosus: the quest for symptom-specific biomarkers.Fukushima journal of medical science · 2020Review
- Different patterns of cerebral perfusion in SLE patients with and without neuropsychiatric manifestations.Human brain mapping · 2020Article
- Evaluation of oxygen extraction fraction in systemic lupus erythematosus patients using quantitative susceptibility mapping.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Article
- Olfactory Dysfunction in CNS Neuroimmunological Disorders: a Review.Molecular neurobiology · 2019Review
- The MRZ reaction helps to distinguish rheumatologic disorders with central nervous involvement from multiple sclerosis.BMC neurology · 2018Article
- A case of neuropsychiatric lupus Erythematosus characterized by the Owl's eye sign: a case report.BMC neurology · 2017Article
- Neuropsychiatric lupus: a mosaic of clinical presentations.BMC medicine · 2015Review
- Neuropsychiatric systemic lupus erythematosus: pathogenesis and biomarkers.Nature reviews. Neurology · 2014Review
- Complete factor I deficiency due to dysfunctional factor I with recurrent aseptic meningo-encephalitis.Journal of clinical immunology · 2013Article
- Corticosteroid-induced neuropsychiatric disorders: review and contrast with neuropsychiatric lupus.Rheumatology international · 2013Review
- Evaluation of vasomotor reactivity in systemic lupus erythematosus patients and its comparison with the control group.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013Article
- Neuropsychiatric lupus.Sultan Qaboos University medical journal · 2013Article
- Blood pressure and vascular dysfunction underlie elevated cerebral blood flow in systemic lupus erythematosus.The Journal of rheumatology · 2012Article
- Article
- Dysregulated expression of CXCR4/CXCL12 in subsets of patients with systemic lupus erythematosus.Arthritis and rheumatism · 2010Article
- Extreme hypoglycorrhachia: not always bacterial meningitis.Nature reviews. Neurology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuropsychiatric syndromes in systemic lupus erythematosus (SLE) have a wide range of severity and phenotype and are fairly common. Presentations are seen involving both central and peripheral nervous systems. Pathogenic mechanisms are thought to include vascular occlusion and hemorrhage, antineuronal antibodies, cytokine effects, choroid plexus dysfunction, neuroendocrine-immune effects, and direct central nervous system (CNS) tissue injury. Work-up includes serum, cerebrospinal fluid (CSF), and imaging studies. Treatment is based on severity and phenotype and includes steroids, anticoagulants, antidepressants, and cytotoxic approaches. Much remains to be done in terms of further elucidation of pathologic processes, correlation of these mechanisms with specific phenotypes, and management of the most severe presentations of neuropsychiatric lupus erythematosus.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.