Evidence map›Paper›PMID 18180804›Full record

ArticleProstate cancer and prostatic diseases2008

Granulomatous prostatitis due to Cryptococcus neoformans: diagnostic usefulness of special stains and molecular analysis of 18S rDNA.

R Wada, N Nakano, N Yajima, T Yoneyama, Y Wakasaya, C Murakami, K Yamato, S Yagihashi

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Prostate cancer and prostatic diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

R WadaDepartment of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. ryuichi@cc.hirosaki-u.ac.jp
N Nakano
N Yajima
T Yoneyama
Y Wakasaya
C Murakami
K Yamato
S Yagihashi
Hirosaki University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 57-year-old Japanese man complained of pain on micturition. The prostate was of normal size but hard. Transrectal needle biopsy demonstrated granulomatous prostatitis with small focal abscesses. Staining with periodic acid-Schiff, Grocott's methenamine silver and Fontana-Masson revealed yeast-form fungus in the granulomas. The mucoid capsule of the fungus stained with mucicarmine. PCR specific for cryptococcal 18S rDNA using DNA extracted from the pathological specimen was positive, and the sequence was homologous to Cryptococcus neoformans. A diagnosis of cryptococcal granulomatous prostatitis was made. The patient was then found to suffer from meningitis and lung abscess, and was treated with amphotericin B and flucytosine. Careful histological and molecular studies are beneficial to reach the correct diagnosis and to prevent an unfavorable outcome of disseminated cryptococcosis.

Indexed as

AbscessAmphotericin BAntifungal AgentsCarmineColoring AgentsCryptococcosisCryptococcus neoformansDNA, FungalDNA, RibosomalDrug Therapy, CombinationFlucytosineGranulomaHumansLung Diseases, FungalMaleMeningitis, CryptococcalAmphotericin BAntifungal AgentsCarmineColoring AgentsDNA, FungalDNA, RibosomalFlucytosineFontana-Masson stainMethenaminemucicarmineRNA, FungalRNA, Ribosomal, 18SSilver Nitrate

Identifiers

PMID18180804
OpenAlexW1963573018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.