Evidence map›Paper›PMID 18180351›Full record

ArticleAntimicrobial agents and chemotherapy2008

Mechanisms of resistance to daptomycin in Enterococcus faecium.

Clemente I Montero, Frida Stock, Patrick R Murray

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 74 citations in OpenAlex.

  1. Exploring Daptomycin Hypersensitivity inInternational journal of molecular sciences · 2025
    Article
  2. Review
  3. Review
  4. Review
  5. Pathogenicity of Enterococci.Microbiology spectrum · 2019
    Review
  6. Review
  7. Review
  8. Rapid emergence of daptomycin resistance in clinical isolates of Corynebacterium striatum… a cautionary tale.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014
    Article
  9. Article
  10. Article
  11. Article
  12. Genetic basis for daptomycin resistance in enterococci.Antimicrobial agents and chemotherapy · 2011
    Article
  13. Emergence of daptomycin-resistant VRE: experience of a single institution.Infection control and hospital epidemiology · 2011
    Article
  14. Daptomycin nonsusceptible enterococci: an emerging challenge for clinicians.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2011
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Clemente I MonteroMicrobiology Service, Department of Laboratory Medicine, Warren G. Magnuson Clinical Center, National Institutes of Health, US Department of Health and Human Services, 10 Center Drive, MSC 1508, Bethesda, Maryland 20892-1508, USA monteroc@cc.nih.gov.
Frida Stock
Patrick R Murray
National Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated the clonal emergence of daptomycin-resistant Enterococcus faecium strains isolated from a patient with leukocyte adhesion deficiency syndrome. The resistance mechanism in these strains is independent of either equivalent point mutations previously described for Staphylococcus aureus or daptomycin inactivation mechanisms identified in soil bacteria.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsBacterial ProteinsDaptomycinDNA, BacterialElectrophoresis, Gel, Pulsed-FieldEnterococcus faeciumGram-Positive Bacterial InfectionsHumansLeukocyte-Adhesion Deficiency SyndromeMicrobial Sensitivity TestsPoint MutationPolymerase Chain ReactionVancomycinAnti-Bacterial AgentsBacterial ProteinsDaptomycinDNA, BacterialVancomycin

Identifiers

PMID18180351
PMCPMC2258551
OpenAlexW2127701647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.