ArticleMolecular microbiology2008
A small protein from the bop-brp intergenic region of Halobacterium salinarum contains a zinc finger motif and regulates bop and crtB1 transcription.
Article in Molecular microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 39 citations in OpenAlex.
- Article
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- Guided tour through the small protein landscape ofmicroLife · 2025Article
- C(P)XCG Proteins ofInternational journal of molecular sciences · 2024Article
- Ion-pumping microbial rhodopsin protein classification by machine learning approach.BMC bioinformatics · 2023Article
- Characterization of the zinc finger μ-protein HVO_0758 fromFrontiers in microbiology · 2023Article
- Archaea Carotenoids: Natural Pigments with Unexplored Innovative Potential.Marine drugs · 2022Review
- Small Proteins in Archaea, a Mainly Unexplored World.Journal of bacteriology · 2022Review
- Proteolysis at the Archaeal Membrane: Advances on the Biological Function and Natural Targets of Membrane-Localized Proteases inFrontiers in microbiology · 2022Review
- Discovery of a small protein factor involved in the coordinated degradation of phycobilisomes in cyanobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Article
- Deciphering Pathways for Carotenogenesis in Haloarchaea.Molecules (Basel, Switzerland) · 2020Article
- Isolation and Taxonomic Characterization of Novel Haloarchaeal Isolates From Indian Solar Saltern: A Brief Review on Distribution of Bacteriorhodopsins and V-Type ATPases in Haloarchaea.Frontiers in microbiology · 2020Article
- Article
- Article
- In silico and experimental improvement of bacteriorhodopsin production in Halobacterium salinarum R1 by increasing DNA-binding affinity of Bat through Q661R/Q665R substitutions in HTH motif.Extremophiles : life under extreme conditions · 2019Article
- Complex Effects of Cytochrome P450 Monooxygenase on Purple Membrane and Bacterioruberin Production in an Extremely Halophilic Archaeon: Genetic, Phenotypic, and Transcriptomic Analyses.Frontiers in microbiology · 2018Article
- Transcriptome analysis of Haloquadratum walsbyi: vanity is but the surface.BMC genomics · 2017Article
- The protein interaction network of a taxis signal transduction system in a halophilic archaeon.BMC microbiology · 2012Article
- Genome-wide responses of the model archaeon Halobacterium sp. strain NRC-1 to oxygen limitation.Journal of bacteriology · 2012Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteriorhodopsin, the photosynthetic protein of Halobacterium salinarum, is optimally expressed under anaerobic growth conditions. We identified Brz (OE3104F, bacteriorhodopsin-regulating zinc finger protein), a new regulator of the bop gene. It is a small protein with a zinc finger motif, encoded directly upstream of the bop gene in the same orientation. Deletion of the brz gene caused a large decrease of bop mRNA levels as shown by Northern blot and microarray analysis. A similar effect was obtained by site-directed mutagenesis of Cys and His residues in the zinc finger motif, indicating the importance of this motif for the function of the protein. In silico analysis of the genomes from H. salinarum and other archaea revealed a large family of similar small zinc finger motif proteins, some of which may also be involved in transcription regulation of their adjacent genes.
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