ArticleThe Plant cell2008
The Arabidopsis small G protein ROP2 is activated by light in guard cells and inhibits light-induced stomatal opening.
Article in The Plant cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 62 citations in OpenAlex.
- The regulation of vacuole morphology in stigma papilla cells is involved in water transfer to pollen in Arabidopsis thaliana.Plant reproduction · 2025Article
- Polar localization and local translation of RHO-RELATED PROTEIN FROM PLANTS2 mRNAs promote root hair growth in Arabidopsis.The Plant cell · 2024Article
- Maize LOST SUBSIDIARY CELL encoding a large subunit of ribonucleotide reductase is required for subsidiary cell development and plant growth.Journal of experimental botany · 2023Article
- The ROP2 GTPase Participates in Nitric Oxide (NO)-Induced Root Shortening in Arabidopsis.Plants (Basel, Switzerland) · 2023Article
- ROP signaling regulates spatial pattern of cell division and specification of meristem notch.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Research Advances in Heterotrimeric G-Protein α Subunits and Uncanonical G-Protein Coupled Receptors in Plants.International journal of molecular sciences · 2021Review
- RIC7 plays a negative role in ABA-induced stomatal closure by inhibiting HPlant signaling & behavior · 2021Article
- Function of membrane domains in rho-of-plant signaling.Plant physiology · 2021Review
- A functionally informed evolutionary framework for the study of LRR-RLKs during stem cell maintenance.Journal of plant research · 2020Article
- Light-Mediated Signaling and Metabolic Changes Coordinate Stomatal Opening and Closure.Frontiers in plant science · 2020Review
- Rho-of-plant activated root hair formation requiresDevelopment (Cambridge, England) · 2019Article
- Glycosylphosphatidylinositol-Anchored Proteins inFrontiers in plant science · 2019Review
- Overexpression of a NovelInternational journal of molecular sciences · 2018Article
- ROP GTPases Structure-Function and Signaling Pathways.Plant physiology · 2018Review
- Article
- The RopGEF2-ROP7/ROP2 Pathway Activated by phyB Suppresses Red Light-Induced Stomatal Opening.Plant physiology · 2017Article
- The Microtubule-Associated Protein MAP18 Affects ROP2 GTPase Activity during Root Hair Growth.Plant physiology · 2017Article
- Differential TOR activation and cell proliferation inProceedings of the National Academy of Sciences of the United States of America · 2017Article
- C-terminal domain (CTD) phosphatase links Rho GTPase signaling to Pol II CTD phosphorylation in Arabidopsis and yeast.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- A NAC Transcription Factor Represses Putrescine Biosynthesis and Affects Drought Tolerance.Plant physiology · 2016Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ROP small G proteins function as molecular switches in diverse signaling processes. Here, we investigated signals that activate ROP2 in guard cells. In guard cells of Vicia faba expressing Arabidopsis thaliana constitutively active (CA) ROP2 fused to red fluorescent protein (RFP-CA-ROP2), fluorescence localized exclusively at the plasma membrane, whereas a dominant negative version of RFP-ROP2 (DN-ROP2) localized in the cytoplasm. In guard cells expressing green fluorescent protein-ROP2, the relative fluorescence intensity at the plasma membrane increased upon illumination, suggesting that light activates ROP2. Unlike previously reported light-activated factors, light-activated ROP2 inhibits rather than accelerates light-induced stomatal opening; stomata bordered by guard cells transformed with CA-rop2 opened less than controls upon light irradiation. When introduced into guard cells together with CA-ROP2, At RhoGDI1, which encodes a guanine nucleotide dissociation inhibitor, inhibited plasma membrane localization of CA-ROP2 and abolished the inhibitory effect of CA-ROP2 on light-induced stomatal opening, supporting the negative effect of active ROP2 on stomatal opening. Mutant rop2 Arabidopsis guard cells showed phenotypes similar to those of transformed V. faba guard cells; CA-rop2 stomata opened more slowly and to a lesser extent, and DN-rop2 stomata opened faster than wild-type stomata in response to light. Moreover, in rop2 knockout plants, stomata opened faster and to a greater extent than wild-type stomata in response to light. Thus, ROP2 is a light-activated negative factor that attenuates the extent of light-induced changes in stomatal aperture. The inhibition of light-induced stomatal opening by light-activated ROP2 suggests the existence of feedback regulatory mechanisms through which stomatal apertures may be finely controlled.
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