Evidence map›Paper›PMID 18178616›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2008

Nanoelectrochemistry of mammalian cells.

Peng Sun, François O Laforge, Thushara P Abeyweera, Susan A Rotenberg, James Carpino, Michael V Mirkin

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Longitudinal transformation of mitochondrial metabolism during neurogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. CytochromeProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Methods to Measure Water Permeability.Advances in experimental medicine and biology · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Scanning Ion Conductance Microscopy.Chemical reviews · 2021
    Review
  12. Article
  13. Nanoneedle-Based Materials for Intracellular Studies.Advances in experimental medicine and biology · 2021
    Article
  14. Nanoelectrochemical quantification of single-cell metabolism.Analytical and bioanalytical chemistry · 2021
    Review
  15. Review
  16. Bioelectrical understanding and engineering of cell biology.Journal of the Royal Society, Interface · 2020
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Peng SunDepartment of Chemistry and Biochemistry, Queens College-City University of New York, Flushing, NY 11367, USA.
François O Laforge
Thushara P Abeyweera
Susan A Rotenberg
James Carpino
Michael V Mirkin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a significant current interest in development of new techniques for direct characterization of the intracellular redox state and high-resolution imaging of living cells. We used nanometer-sized amperometric probes in combination with the scanning electrochemical microscope (SECM) to carry out spatially resolved electrochemical experiments in cultured human breast cells. With the tip radius approximately 1,000 times smaller than that of a cell, an electrochemical probe can penetrate a cell and travel inside it without apparent damage to the membrane. The data demonstrate the possibility of measuring the rate of transmembrane charge transport and membrane potential and probing redox properties at the subcellular level. The same experimental setup was used for nanoscale electrochemical imaging of the cell surface.

Indexed as

BreastCell Line, TumorCell MembraneElectrochemistryElectrodesGoldHumansMembrane PotentialsMicroscopy, Electron, ScanningModels, TheoreticalNanotechnologyOxidation-ReductionOxidative StressGold

Identifiers

PMID18178616
PMCPMC2206555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.