ReviewCurrent opinion in structural biology2008
Unveiling substrate RNA binding to H/ACA RNPs: one side fits all.
Review in Current opinion in structural biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Many Functions of Telomerase Components: Certainties, Doubts, and Inconsistencies.International journal of molecular sciences · 2022Review
- The presence of the ACA box in archaeal H/ACA guide RNAs promotes atypical pseudouridylation.RNA (New York, N.Y.) · 2020Article
- Structure-function relationships of archaeal Cbf5 during in vivo RNA-guided pseudouridylation.RNA (New York, N.Y.) · 2016Article
- A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome.BMC medical genetics · 2014Article
- Targeting vertebrate intron-encoded box C/D 2'-O-methylation guide RNAs into the Cajal body.Nucleic acids research · 2014Article
- Progress in structural studies of telomerase.Current opinion in structural biology · 2014Review
- Mechanism of the AAA+ ATPases pontin and reptin in the biogenesis of H/ACA RNPs.RNA (New York, N.Y.) · 2012Article
- Human intron-encoded Alu RNAs are processed and packaged into Wdr79-associated nucleoplasmic box H/ACA RNPs.Genes & development · 2012Article
- An enhanced H/ACA RNP assembly mechanism for human telomerase RNA.Molecular and cellular biology · 2012Article
- It all comes together at the ends: telomerase structure, function, and biogenesis.Mutation research · 2012Review
- Pre-steady-state kinetic analysis of the three Escherichia coli pseudouridine synthases TruB, TruA, and RluA reveals uniformly slow catalysis.RNA (New York, N.Y.) · 2011Article
- The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic.Genes & development · 2011Article
- Pseudouridine formation in archaeal RNAs: The case of Haloferax volcanii.RNA (New York, N.Y.) · 2011Article
- The box H/ACA snoRNP assembly factor Shq1p is a chaperone protein homologous to Hsp90 cochaperones that binds to the Cbf5p enzyme.Journal of molecular biology · 2009Article
- Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA.Nature structural & molecular biology · 2009Article
- SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs.RNA (New York, N.Y.) · 2009Article
- Long-distance placement of substrate RNA by H/ACA proteins.RNA (New York, N.Y.) · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The H/ACA RNP pseudouridylases function on a large number of extraordinarily complex RNA substrates including pre-ribosomal and small nuclear RNAs. Recent structural data show that H/ACA RNPs capture their RNA substrates via a simple one-sided attachment model. However, the precise placement of each RNA substrate into the active site of the catalytic subunit relies on the essential functions of the RNP proteins. The specific roles of each H/ACA RNP protein are being elucidated by a combination of structural and biochemical studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.