Evidence map›Paper›PMID 18178073›Full record

ReviewCurrent opinion in cell biology2008

Structural and regulatory roles of nonmotor spindle proteins.

Amity L Manning, Duane A Compton

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. eLife · 2017
    Article
  3. Article
  4. Oncology letters · 2017
    Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Amity L ManningDepartment of Biochemistry, Dartmouth Medical School, Hanover, NH 03755, USA. amity.l.manning@dartmouth.edu
Duane A Compton
Dartmouth College · US

Funding

Organization of the Mammalian Mitotic SpindleR37GM051542 · NIGMS · DARTMOUTH COLLEGE · PI COMPTON, DUANE A. · 2013 to 2022
$6.7M
Organization of the Mammilian Mitotic SpindleR01GM051542 · NIGMS · DARTMOUTH COLLEGE · PI COMPTON, DUANE A. · 1996 to 2012
$4.6M
NIGMS NIH HHS GM 51542NIGMS NIH HHS R01 GM051542NIGMS NIH HHS R37 GM051542
6 · The paper itself

Abstract

Chromosome alignment and segregation during cell division rely on a highly ordered bipolar microtubule array called the mitotic spindle. The organization of microtubules into bipolar spindles with focused poles during mitosis requires numerous microtubule-associated proteins including both motor and nonmotor proteins. Nonmotor microtubule-associated proteins display extraordinary diversity in how they contribute to mitotic spindle organization. These mechanisms include regulation of microtubule nucleation and organization, direct and indirect influences on motor function, and control of cell cycle progression. Furthermore, many nonmotor spindle proteins display altered expression in cancer cells emphasizing their important roles in cell proliferation.

Indexed as

AnimalsCell CycleCross-Linking ReagentsHumansMicrotubule-Associated ProteinsMicrotubulesMolecular Motor ProteinsSpindle ApparatusCross-Linking ReagentsMicrotubule-Associated ProteinsMolecular Motor Proteins

Identifiers

PMID18178073
PMCPMC2289991
OpenAlexW2061420234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.