Evidence map›Paper›PMID 18176832›Full record

SynthesisObesity surgery2008

Vitamin D and the bariatric surgical patient: a review.

Charlene W Compher, Karen O Badellino, Joseph I Boullata

Registry-linked trialAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Obesity surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01385098 (Preoperative Vitamin D Status and Efficacy of Therapeutic Vitamin D Supplementation Postoperatively in Bariatric Surgery Patients), which is not on this map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01385098 nacompletednot on this mapstarted 2011, after this paper: background citation

Preoperative Vitamin D Status and Efficacy of Therapeutic Vitamin D Supplementation Postoperatively in Bariatric Surgery Patients

TypeinterventionalSponsorVadim Sherman, MDRan2011 to 2015Enrolled37ConditionsObesity, Vitamin D DeficiencyArmsVitamin D3 and Calcium
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 113 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. VITAMIN D LEVELS AND LIPID PROFILE IN PATIENTS UNDERGOING BARIATRIC SURGERY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023
    Article
  7. Review
  8. Review
  9. Review
  10. Observational
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  14. Review
  15. Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Charlene W CompherUniversity of Pennsylvania School of Nursing, 418 Curie Boulevard, Philadelphia, PA 19104-6096, USA. compherc@nursing.upenn.edu
Karen O Badellino
Joseph I Boullata
University of Pennsylvania · USHospital of the University of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAdiposity has been inversely associated with vitamin D concentration across a range of body mass index values and cultural groups. As obesity has increased markedly worldwide, a greater number of patients with severe obesity have been treated with gastric restrictive and/or malabsorptive surgical procedures. The purpose of this review was to describe current knowledge about vitamin D and severe obesity, and the impact of obesity surgery on vitamin D status. RESEARCH METHODS AND PROCEDURES: A systematic review was conducted with search terms obesity, vitamin D, osteoporosis, bone disease, gastric bypass, and obesity surgery in various combinations. Publications were limited to those since 2000 to control for similarity in vitamin D assays and obesity prevalence levels.

resultsMean 25-hydroxy vitamin D was <80 nmol/l in more than 1,900 patients preoperatively, and was not restored to the optimal concentration of >80 nmol/l postoperatively. Both secondary hyperparathyroidism and bone loss were common, particularly when the obesity surgery included a malabsorptive component. Standard postsurgical supplementation with vitamin D and calcium have not been adequate to suppress secondary hyperparathyroidism or to restore 25-hydroxy vitamin D status. DISCUSSION: The mechanisms behind vitamin D deficiency in severe obesity and evidence-based corrective actions have not been well-defined. Of particular concern are adolescents who qualify for and elect surgical treatment of their obesity, where subsequent metabolic bone disease may be long-standing.

Indexed as

Bariatric SurgeryBone DensityHumansObesity, MorbidVitamin DVitamin D DeficiencyVitamin D

Identifiers

PMID18176832
OpenAlexW2091443307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.