ArticleParasitology research2008
Isolation and identification of mosquito larvicidal compound from Abutilon indicum (Linn.) Sweet.
Article in Parasitology research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed.
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- Chemical analysis, repellent, larvicidal, and oviposition deterrent activities of plant essential oils againstFrontiers in insect science · 2025Article
- Chemical composition and toxicity of commercial Mentha spicata and Eucalyptus citriodora essential oils on Culex quinquefasciatus and non-target insects.Environmental science and pollution research international · 2024Article
- Bioactivity of Fractions and Pure Compounds fromPlants (Basel, Switzerland) · 2023Article
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- Plants of the Genus Zingiber: A Review of Their Ethnomedicine, Phytochemistry and Pharmacology.Molecules (Basel, Switzerland) · 2022Review
- Chemical Composition and Insecticidal, Antiplasmodial, and Anti-Leishmanial Activity ofEvidence-based complementary and alternative medicine : eCAM · 2022Article
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- Insecticidal, Antimalarial, and Antileishmanial Effects of Royal Jelly and Its Three Main Fatty Acids,Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Insecticidal Activity and Free Radical Scavenging Properties of Isolated Phytoconstituents from the Saudi PlantMolecules (Basel, Switzerland) · 2021Article
- Renoprotective effects of cinnamon oil against APAP-Induced nephrotoxicity by ameliorating oxidative stress, apoptosis and inflammation in rats.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2021Article
- Phytomolecules-Coated NiO Nanoparticles Synthesis UsingInternational journal of nanomedicine · 2021Article
- Antiparasitic effects of ethanolic extracts ofParasitology · 2020Article
- Protective effect of leaf extract ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020Article
- Green Synthesis of MnO Nanoparticles UsingBiomolecules · 2020Article
- Evaluation of larvicidal activity of esters of 4-mercapto-2-butenoic acid againstSaudi journal of biological sciences · 2019Article
- Article
- A Review of Resistance Mechanisms of Synthetic Insecticides and Botanicals, Phytochemicals, and Essential Oils as Alternative Larvicidal Agents Against Mosquitoes.Frontiers in physiology · 2019Review
- Zingiber cernuum (Zingiberaceae) essential oil as effective larvicide and oviposition deterrent on six mosquito vectors, with little non-target toxicity on four aquatic mosquito predators.Environmental science and pollution research international · 2018Article
3 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
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Abstract
Larvicidal activity of crude hexane, ethyl acetate, petroleum ether, acetone and methanol extracts of five medicinal plants, Abutilon indicum, Aegle marmelos, Euphorbia thymifolia, Jatropha gossypifolia and Solanum torvum were assayed for their toxicity against the early fourth-instar larvae of Culex quinquefasciatus. The larval mortality was observed after 24 h exposure. All extracts showed moderate larvicidal effects; however, the highest larval mortality was found in petroleum ether extract of A. indicum. In the present study, bioassay-guided fractionation of A. indicum led to the separation and identification of a beta-sitosterol as a potential new mosquito larvicidal compound with LC50 value of 11.49, 3.58 and 26.67 ppm against Aedes aegypti L, Anopheles stephensi Liston and C. quinquefasciatus Say (Diptera: Culicidae), respectively. 1H NMR, 13C NMR and mass spectral data confirmed the identification of the active compound. beta-sitosterol has been recognized as the active ingredient of many medicinal plant extracts. All the crude extracts when screened for their larvicidal activities indicated toxicity against the larvae of C. quinquefasciatus. This article reports the isolation and identification of the beta-sitosterol as well as bioassay data for the crude extracts. There are no reports of beta-sitosterol in the genus A. indicum, and their larvicidal activities are being evaluated for the first time. Results of this study show that the petroleum ether extract of A. indicum may be considered as a potent source and beta-sitosterol as a new natural mosquito larvicidal agent.
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