ArticleExtremophiles : life under extreme conditions2008
Mutation and reversion frequencies of different Sulfolobus species and strains.
Article in Extremophiles : life under extreme conditions, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Article
- The biology of thermoacidophilic archaea from the order Sulfolobales.FEMS microbiology reviews · 2021Article
- Genetic Control of Oxidative Mutagenesis inJournal of bacteriology · 2020Article
- Functional Analysis of the NucS/EndoMS of the Hyperthermophilic ArchaeonFrontiers in microbiology · 2020Article
- How a Genetically Stable Extremophile Evolves: Modes of Genome Diversification in the Archaeon Sulfolobus acidocaldarius.Journal of bacteriology · 2017Article
- Article
- Understanding DNA Repair in Hyperthermophilic Archaea: Persistent Gaps and Other Reasons to Focus on the Fork.Archaea (Vancouver, B.C.) · 2015Review
- Endogenous mutagenesis in recombinant sulfolobus plasmids.Journal of bacteriology · 2013Article
- Inducible and constitutive promoters for genetic systems in Sulfolobus acidocaldarius.Extremophiles : life under extreme conditions · 2010Article
- MutS and MutL are dispensable for maintenance of the genomic mutation rate in the halophilic archaeon Halobacterium salinarum NRC-1.PloS one · 2010Article
- Accurate DNA synthesis by Sulfolobus solfataricus DNA polymerase B1 at high temperature.Extremophiles : life under extreme conditions · 2010Article
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
We have determined the apparent and actual spontaneous mutation frequencies and rates for different species and strains of the thermoacidophilic crenarchaeote Sulfolobus. The proportion of mutations caused by insertion sequences has also been analyzed. Mutation frequencies for S. islandicus (0.08-0.6 mutations per cell division and 10(7) cells) were below those determined for S. solfataricus and comparable to or lower than those for S. acidocaldarius. The proportion of insertion sequence mutations for the S. islandicus strains REN1H1 (9 out of 230) and HVE10/4 (0 out of 24) was found to be considerably lower than in S. solfataricus P1 and P2 and also low in comparison to other S. islandicus strains. Mutants defective in either the pyrEF genes or the lacS gene have been isolated. Their growth phenotype on selective and non-selective medium was examined and the inactivating mutations in either of the genes were determined. In addition the reversion frequencies for these mutants were measured and found to be in the range of <0.6-1.5 mutations per cell division and 10(8) cells. However, when being subjected to electroporation as a transformation procedure, increased reversion was observed.
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