Evidence map›Paper›PMID 18175059›Full record

SynthesisClinical and experimental nephrology2008

Delivery patterns of recommended chronic kidney disease care in clinical practice: administrative claims-based analysis and systematic literature review.

Marie D Philipneri, Lisa A Rocca Rey, Mark A Schnitzler, Kevin C Abbott, Daniel C Brennan, Steven K Takemoto, Paula M Buchanan, Thomas E Burroughs, Lisa M Willoughby, Krista L Lentine

Registry-linked trialAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Clinical and experimental nephrology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00921687 (Chronic Kidney Disease Guideline Adherence - a Cluster Randomized Controlled Quality Improvement Study), which is not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00921687 nacompletednot on this mapstarted 2009, after this paper: background citation

Chronic Kidney Disease Guideline Adherence - a Cluster Randomized Controlled Quality Improvement Study

TypeinterventionalSponsorLouis Stokes VA Medical CenterRan2009 to 2010Enrolled781ConditionsChronic Renal InsufficiencyArmsEducation only, Multifactorial intervention
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Automated clinical reminders for primary care providers in the care of CKD: a small cluster-randomized controlled trial.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2011
    Trial
  5. Cost-effectiveness analysis of a randomized trial comparing care models for chronic kidney disease.Clinical journal of the American Society of Nephrology : CJASN · 2011
    Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Nephrology comanagement and the quality of antibiotic prescribing in primary care for patients with chronic kidney disease: a retrospective cross-sectional study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2019
    Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Implementation of a CKD checklist for primary care providers.Clinical journal of the American Society of Nephrology : CJASN · 2014
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marie D PhilipneriDivision of Nephrology, Saint Louis University School of Medicine, St Louis, MO 63104, USA.
Lisa A Rocca Rey
Mark A Schnitzler
Kevin C Abbott
Daniel C Brennan
Steven K Takemoto
Paula M Buchanan
Thomas E Burroughs
Lisa M Willoughby
Krista L Lentine

Funding

Polyomavirus and Mentoring in Renal TransplantationK24DK002886 · NIDDK · WASHINGTON UNIVERSITY · PI BRENNAN, DANIEL CONLON · 2003 to 2012
$1.5M
Cardiovascular Risk Prediction after Kidney TransplantK08DK073036 · NIDDK · SAINT LOUIS UNIVERSITY · PI LENTINE, KRISTA L · 2006 to 2010
$668k
NIDDK NIH HHS K08-DK073036NIDDK NIH HHS K24-DK002886
6 · The paper itself

Abstract

backgroundClinical practice guidelines for management of chronic kidney disease (CKD) have been developed within the Kidney Disease Outcomes Quality Initiative (K/DOQI). Adherence patterns may identify focus areas for quality improvement.

methodsWe retrospectively studied contemporary CKD care patterns within a private health system in the United States, and systematically reviewed literature of reported practices internationally. Five hundred and nineteen patients with moderate CKD (estimated GFR 30-59 ml/min) using healthcare benefits in 2002-2005 were identified from administrative insurance records. Thirty-three relevant publications in 2000-2006 describing care in 77,588 CKD patients were reviewed. Baseline demographic traits and provider specialty were considered as correlates of delivered care. Testing consistent with K/DOQI guidelines and prevalence of angiotensin converting enzyme inhibitor/angiotensin receptor blocker (ACEi/ARB) medication prescriptions were ascertained from billing claims. Care descriptions in the literature sample were based on medical charts, electronic records and/or claims.

resultsKDOQI-consistent measurements of parathyroid hormone (7.1 vs. 0.6%, P = 0.0002), phosphorus (38.2 vs. 1.9%, P < 0.0001) and quantified urinary protein (23.8 vs. 9.4%, P = 0.008) were more common among CKD patients with versus without nephrology referral in the administrative data. Nephrology referral correlated with increased likelihood of testing for parathyroid hormone and phosphorus after adjustment for baseline patient factors. Use of ACEi/ARB medications was more common among patients with nephrology contact (50.0 vs. 30.0%; P = 0.008) but appeared largely driven by higher comorbidity burden. The literature review demonstrated similar practice patterns.

conclusionsDelivery of CKD care may be monitored by administrative data. There is opportunity for improvement in CKD guideline adherence in practice.

Indexed as

Guideline AdherenceAdolescentAdultAgedAged, 80 and overAngiotensin-Converting Enzyme InhibitorsAngiotensin II Type 1 Receptor BlockersComorbidityCreatinineDiabetes ComplicationsDyslipidemiasFemaleHumansHypertensionInsurance Claim ReviewKidney Failure, ChronicAngiotensin-Converting Enzyme InhibitorsAngiotensin II Type 1 Receptor BlockersCreatinineParathyroid Hormone

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.